first_imgInstead of: He’s wheelchair bound. He has a cognitive disability. She receives special ed services. He has a disability. She has autism. He’s handicapped. People jumpingImagine that you have a disability.  You also think of yourself as an artist, a brother, a pizza lover, and a table tennis champion.  Your disability does not define who you are.  Unfortunately, labels are often placed on people with disabilities and they can carry negative connotations.  Saying that someone is “handicapped” immediately lumps them into a vague category that suggests huge limitations. At Easter Seals Crossroads, we encourage People First Language.  Here are some examples: He uses a wheelchair.center_img She has a brain injury. Acceptable Term: She’s autistic. She’s brain damaged. He’s mentally retarded. She’s a special ed kid. As you can see, People First Language puts emphasis on the person you are talking about, not their disability.  This promotes respectful language to use when addressing people who happen to have disabilities.For more information and examples, visit Disability is Natural.Share this…TwitterFacebookPinterestLinkedInEmailPrint RelatedIt All Starts With a Dream: Spotlight on Laura MedcalfJuly 23, 2014In “Easter Seals Crossroads”Travel Series: Flying with Southwest AirlinesNovember 24, 2010In “Services”2015 marks key year for workers accommodationsOctober 28, 2015In “Communication”last_img read more

first_imgLooking for a fun timer for your child or student who doesn’t yet understand the length of time?  Mouse Timer from LITALICO expresses the length of time using a cute little mouse gnawing on apples.Finding the right timing tool for students can be challenging.  This is especially true for those with autism or others who cannot tolerate loud noises nor the ticking of traditional timers.  Because this app simply features a cute mouse gnawing on apples, it is able to benefit a myriad of individuals.Additionally, it’s an app that allows children to “see” the length of time.  This allows them to better understand the overall concept of time.  Mouse Timer can be used as an educational tool as well as an everyday timer!  It can help individuals completing the following tasks:HomeworkReadingEating (for those picky eaters who spend most of their time picking around their food)ExercisingChoresAnd more!Features of Mouse Timer:Easy-to-use: simply select a timeDeveloped by teachers and professors who specialize in children’s development and educationRuns in background so users can multitask;Once time is up, a notification will pop up App has no advertisements so there are no visual distractions for childrenCan be used for free (in-app purchase allows you to select white mouse instead of gray mouse)Ability to pause and resume the timerAvailable on both iTunes and Google PlayVisit the LITALICO Inc. website to learn more.Share this…TwitterFacebookPinterestLinkedInEmailPrint Related5 Time Management Tools for Special NeedsJanuary 17, 2018In “Autism”AM264 – Time TimerDecember 8, 2017In “Accessibility Minute”Time Timer – Visual TimerDecember 5, 2017In “Products and Devices”last_img read more

first_imgStein Mart, a national specialty off-price retailer, has gained a holistic view of its inventory and a more streamlined approach to merchandise planning with Oracle Cloud. Merchandise Financial Planning Helps National Retailer Leverage Data to Optimize Inventory Management Stein Mart Boosts Omni-Channel Growth with Oracle Cloud Business WireJune 24, 2019, 9:02 pmJune 24, 2019 By consolidating the planning and forecasting process for its physical stores, online store and warehouses into one solution, Stein Mart will be better equipped to manage its inventory to support the needs of its customers, regardless of how they choose to shop. With Oracle Retail Cloud Services, Stein Mart has the tools to keep its merchandise assortments fresh and relevant for buyers. “We have been focused on simplifying our merchandising processes while expanding our omni-channel capabilities and new business initiatives. The enhanced functionality of Oracle’s Merchandise Financial Planning solution will help us analyze data faster to create better plans up front so we can buy smarter and manage inventory more effectively,” said Nick Swetonic, Stein Mart’s senior vice president of planning and allocation.Marketing Technology News: Global Software Leaders Xero and Stripe Join Forces to Bring Seamless Payments to Millions of Small Businesses“Today, retailers sell whatever they buy, often at the expense of the bottom line. Tomorrow, they will be able to more accurately predict placement, price, and sizes across every store and market. This is the promise of the Oracle Retail Cloud,” noted Mike Webster, senior vice president and general manager, Oracle Retail. “We are helping companies like Stein Mart refine their approach to inventory and purchasing, so they can continually delight customers while improving results with merchandise that turns quickly.”Marketing Technology News: GoSpotCheck Gains Valuable Leadership Expertise with Five Additions to Management TeamStein Mart partnered with Cognira, experts in analytics, configuration and integration, and retail consulting firm The Parker Avery Group to re-engineer business processes and implement Oracle Retail Merchandise Financial Planning Cloud Service. Both Cognira and Parker Avery are members of the Oracle PartnerNetwork (OPN). Previously, Stein Mart also implemented Oracle Retail Merchandising, Oracle Retail Store Inventory Management, Oracle GoldenGate, Oracle JD Edwards, and Oracle Retail Point of Sale.Marketing Technology News: Medallia Names Software Industry Veteran Rob Bernshteyn to its Board of Directors Stein Mart storefront CogniraMarketing Technology NewsNewsOracle CloudOracle Retail CloudParker AveryStein Mart Previous ArticleHow to Increase Your Productivity with Proper Time Management?Next ArticleCoSchedule Launches Marketing Suite to Transform the Way Marketers Worklast_img read more

first_img The Real Reason Emma Watson Refuses to Do a Nude Scene Prime Day is officially over, but it seems someone forgot to tell that to Amazon, Dell, and Walmart. There are still tons of excellent deals available with huge discounts, but for how much longer no one can say. If you missed out on buying anything during the shopping event, here’s a list of deals that you can still take advantage of.Samsung Galaxy S10 Factory Unlocked w/ 128GB Storage ($599.99) During Amazon’s Prime Day sale you can get one of Samsung’s Galaxy S10 smartphones with 128GB of storage marked down from $899.99 to $599.99. This phone is one of the fastest smartphones available on the market today with a high-end Qualcomm Snapdragon 855 SoC and 8GB of RAM. It also features a relatively high-quality camera and it comes fully unlocked.Apple AirPods w/Wireless Charging Case ($169.99)This set of Apple’s AirPods comes with a wireless charging case. Simply set the earbuds into the case whenever you are finished using them and they will automatically start charging. They also have support for Siri to quickly access your iPhone, and they can last for over 24 hours while listening to music. Amazon is offering these AirPods currently marked down from $199.00 to $169.99.Overpowered DTW2 Intel Core i7-8700 Gaming Desktop w/ Nvidia GTX 1080, 512GB SSD, 2TB HD, 32GB RAM ($899.00)Overpowered’s DTW2 desktop comes loaded with high-performance components at an unbelievable price. At its heart rests an Intel Core i7-8700 and an Nvidia GeForce GTX 1080 graphics card. Best of all, this system is marked down from $1,899.00 to $899.00 at Walmart. Discounted as much as it is, it would be impossible to build a system to match it without paying more. The system appears to have some cooling issues, however, so you should probably plan to buy a few extra case fans or switch the hardware to a different case entirely if you buy it.Featured DealsAmazon Echo Dot 3rd Gen Smart Speaker for $24.99 at Amazon (list price $49.99).Apple iPad 32GB 9.7″ Retina WiFi Tablet (2018 Model) for $249 at Walmart (list price $329).Apple AirPods with Wireless Charging Case for $169.99 at Amazon (list price $199).Apple Watch Series 4 44mm GPS Smartwatch for $359.99 at Amazon (Select “Free No-Rush Shipping” at checkout – list price $429).Samsung Galaxy S10e 128GB 5.8″ Unlocked Smartphone for $549.99 at Amazon (list price $749.99).Google Pixel 3 XL 128GB 6.3″ Unlocked Smartphone for $779.99 at Amazon (list price $999).ASUS ROG Strix Intel Core i5-9300H 6-Core 15.6″ 1080p 120Hz Laptop with GTX 1660Ti, 512GB SSD for $899 at Walmart (list price $1299.99).Dell Vostro 15 5000 Intel Core i5-8265U Quad-core 15.6″ 1080p Win10 Pro Laptop with 256GB SSD for $559 at Dell (list price $1127.14).Dell XPS 8930 Intel Core i7-8700 6-core Tower Desktop with 16GB RAM for $699.99 at Dell (use code: AFF300XPS – list price $999.99).Dell Inspiron 5676 AMD Ryzen 7 2700 8-core Gaming Desktop with Radeon RX 580, 16GB RAM for $699.99 at Dell (list price $1199.99).Prime Exclusive: Free 3 Months Kindle Unlimited at Amazon (list price $29.97).Prime Exclusive: 66% off 3 Months Audible Membership for $14.85 at Amazon (list price $44.85).50% off 1 Year of IPVanish VPN for $39 at IPVanish (list price $77.99).Check out more deals from TechBargains. ElectronicsApple AirPods with Wireless Charging Case for $169.99 at Amazon (list price $199).Apple AirPods with Charging Case for $144.99 at Amazon (list price $159).Apple Watch Series 4 44mm GPS Smartwatch for $359.99 at Amazon (Select “Free No-Rush Shipping” at checkout – list price $429).Samsung Galaxy S10e 128GB 5.8″ Unlocked Smartphone for $549.99 at Amazon (list price $749.99).Google Pixel 3 XL 128GB 6.3″ Unlocked Smartphone for $779.99 at Amazon (list price $999).Ultimate Ears BLAST Portable WiFi Bluetooth Wireless Speaker for $69.99 at Dell (list price $179.99).Ultimate Ears WONDERBOOM Portable Waterproof Bluetooth Speaker for $44.99 at Dell (list price $99.99).More Electronics & Tech Deals here. Smart Home Devices and ServicesPrime Exclusive: Free 3 Months Kindle Unlimited at Amazon (list price $29.97).Prime Exclusive: 66% off 3 Months Audible Membership for $14.85 at Amazon (list price $44.85).20% off Kindle Unlimited 6-Month Subscription (33% off 12-Months, 40% off 24-Months) at Amazon.Prime Exclusive: 1 Year Audible Gold Membership + $0.99 Echo Dot for $119.50 at Amazon (list price $149.50).Amazon Echo Dot 3rd Gen Smart Speaker for $24.99 at Amazon (list price $49.99).Google Home Mini Smart Speaker for $25 (2-Pack for $48) at Walmart (list price $49).Google Home Smart Speaker for $69 at Walmart (list price $129).Google Home Max Smart Speaker + Google Home Mini for $244 at Walmart (Scroll down to “Buy Together and Save” – list price $448).Google Nest Hub 7″ Smart Display for $79 at Walmart (list price $149).Google Nest Hello Smart WiFi Video Doorbell for $189 at Walmart (list price $229).More Smart Home Device Deals here. Laptop & Desktop ComputersApple iPad 32GB 9.7″ Retina WiFi Tablet (2018 Model) for $249 at Walmart (list price $329).Apple iPad Pro 10.5″ 64GB WiFi Tablet for $474 (256GB for $599, 512GB for $699) at Walmart (list price $649).Apple iPad Pro 12.9″ 64GB Tablet (Current Gen with A12x Chip) for $799.99 at Amazon (Discount seen at checkout – list price $999.99).Apple Macbook Air 8th Gen Intel Core i5 13.3″ 2560×1600 Retina Display Laptop with 256GB SSD for $1099.99 at Amazon (list price $1399).ASUS ROG Strix Intel Core i5-9300H 6-Core 15.6″ 1080p 120Hz Laptop with GTX 1660Ti, 512GB SSD for $899 at Walmart (list price $1299.99).Dell Vostro 15 5000 Intel Core i5-8265U Quad-core 15.6″ 1080p Win10 Pro Laptop with 256GB SSD for $559 at Dell (list price $1127.14).Dell Vostro 14 5000 Intel Core i7-8565U Quad-Core 14″ 1080p Laptop with 16GB RAM, 512GB SSD for $779 at Dell (list price $1570).Dell XPS 8930 Intel Core i7-8700 6-core Tower Desktop with 16GB RAM for $699.99 at Dell (use code: AFF300XPS – list price $999.99).Dell Inspiron 5676 AMD Ryzen 7 2700 8-core Gaming Desktop with Radeon RX 580, 16GB RAM for $699.99 at Dell (list price $1199.99).Alienware Aurora R8 Intel Core i7-9700K 8-core Gaming Desktop with RTX 2070 OC, 16GB RAM, 256GB SSD for $1399.99 at Dell (list price $1929.99).Alienware m15 Intel Core i7-8750H 6-Core 15.6″ 144Hz 1080p IPS Laptop with GTX 1060 6GB, 16GB RAM, 512GB SSD for $1199.99 at Dell (use code: AFF680m15 – list price $1879.99).Gigabyte Aero Intel i9-8950HK 6-Core + RTX 2070 144Hz 15″ 1080p Ultraportable Gaming Laptop with 1TB SSD, 16GB RAM for $1799 at Walmart (list price $2399).Dell XPS 15 9570 Intel Core i7-8750H 6-Core 15.6″ 4K Touch Laptop with GTX 1050 Ti, 16GB RAM, 512GB SSD for $1479.99 at Dell (use code: DBLTXPS15 – list price $1849.99).Dell G7 15 Intel Core i7-9750H 6-core 15.6″ 1080p IPS Gaming Laptop with GTX 1660 Ti for $999.99 at Dell (list price $1349.99).Dell New Inspiron 15 5000 Intel Core i5-8265U Quad-core 15.6″ 1080p Laptop with 256GB SSD for $499.99 at Dell (list price $669.99).Dell New Inspiron 3670 Intel Core i5-9400 6-core Desktop with 12GB RAM for $499.99 at Dell (list price $649.99).Dell Inspiron 14 5000 2-in-1 Intel Core i3-8145U 14″ Touch Laptop for $449.99 at Dell (list price $529.99).Dell Vostro 14 3000 Intel Core i3-7020U 14″ Win10 Pro Laptop for $299 at Dell (use code: SMLBIZ299 – list price $780.42).OVERPOWERED DTW2 Intel Core i7-8700 6-Core Gaming Desktop with GTX 1080, 32GB RAM, 512GB SSD + 2TB HDD for $899 at Walmart (list price $1899).OVERPOWERED DTW1 Intel Core i7-8700 6-Core Gaming Desktop with GTX 1070, 16GB RAM, 256GB SSD + 2TB HDD for $699 at Walmart (list price $1399).Dell S2716DG 27″ 144Hz 2560×1440 G-Sync Gaming Monitor for $399.99 at Dell (list price $799.99).Dell UltraSharp U2412M 24″ 1920×1200 IPS Monitor + $100 Dell Gift Card for $249.99 at Dell (list price $339.99).More Laptops & Desktop PC Deals here. 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Tools & Home Improvement, Kitchen Gadgets, and moreInstant Pot DUO60 6-Qt 1000W 7-in-1 Electric Pressure Cooker for $49.99 at Amazon (list price $99.95).Instant Pot Ultra 6-Qt 10-in-1 Electric Pressure Cooker for $87.99 at Amazon (list price $149.95).Today Only: Bissell 86T3 Big Green Professional Carpet Cleaner for $299.99 at Amazon (list price $429.99).Note: Terms and conditions apply. See the relevant retail sites for more information. For more great deals, go to our partners at TechBargains.com. Bran’s Deleted ‘GoT’ Scene Would Have Changed Everything J.K. Rowling Confirms a Hermione Theory We Suspected All Along Amazon Prime Day After Hours Sale: Samsung Galaxy 10e $599.99, Apple AirPods w/ Wireless Charging Case $169.99, GTX 1080 Gaming Desktop $899 1 Comment Sun Baby From ‘Teletubbies’ Is 22 Now & Unrecognizably Gorgeous Directors Just Hinted At a Major Return From ‘Endgame’ By Michael Sexton on July 17, 2019 at 3:33 pm Things Only Adults Notice in ‘ThunderCats’ Maisie Williams’ Transformation is Turning Heads Extremetech may earn affiliate commissions from the shopping links included on this page. To find out more, read our complete terms of use. You Might Also LikePowered By ZergNet The First ‘Scary MCU Film’ Will Come Out During Phase 4 Facebook Twitter Linkedin Pinterest Google Plus Reddit Hacker News Flipboard Email Copy 0shares This site may earn affiliate commissions from the links on this page. Terms of use. Tagged In et deals Post a Comment 1 Commentlast_img read more

first_imgLuokung Technology Corp. (LKCO) (“Luokung” or the “Company”), a leading global spatial-temporal big-data technology company and a leading interactive location-based services company in China, announced that it has signed a stock purchase agreement to acquire 67.36% of Beijing BotBrain AI Technology Ltd and BOTBRAIN AI LIMITED (collectively “BotBrain “).The Company will invest RMB 20 million to BotBrain and will issue 804,162 ordinary shares at USD $7 per share to the former institution investors of BotBrain to obtain 67.36% (the “Acquisition”). The 32.64% share equity of BotBrain will be remained by Mr. Xueyu Lu, the founder and CEO of BotBrain, along with BotBrain ‘s core team members. After the Acquisition, Mr. Lu will continue as CEO of BotBrain AI.BotBrain was established in January 2016, and it has been becoming an advanced provider for intelligent content solutions in China. It’s artificial intelligence algorithms and technology are applied in Chinese semantic analysis, intelligent voice interaction, knowledge graph learning, personalized contents recommendation and other related big data analysis.There are two independent business brands in BotBrain. “Max” content brain is an AI content management and operation platform, which provides AI solutions based on its content services. “BotBrain Zhiyu” is an AI knowledge learning assistant system.Marketing Technology News: Acquia Acquires Mautic to Deliver First-Ever Open Marketing CloudBotBrain has been serving many well-known enterprises based in China, including People’s Daily Overseas, ChinaNews, Kaishu Story, Baby Tree, Baofeng, Bank of China, State Grid, FAW, CreditEase, Facebank and Kingsoft Cloud etc., which involve various industries including media, mobile internet, banking, automobile, financial services, retails and energy.BotBrain has started the cooperation with the Company in technology supports prior the Acquisition, it provides intelligent geographic information algorithms service for us, and Its technology of semantic analysis, knowledge graph and personalized contents recommendation significantly supports the LBS service of Luokung. After the Acquisition, BotBrain will put more investment in the research of intelligent spatial temporal data algorithm and application. BotBrain will provide critical intelligent technologies and application experiences to support our LBS business, personalized full-vector map, and enable us to improve the services we provide to mobile Internet industry and users. Therefore, the Company’s LBS business platform is able to gain a greater competitive advantage.Marketing Technology News: Mareana Named a 2019 Gartner Cool Vendor in Artificial Intelligence Across the Supply ChainThe founder and CEO of BotBrain, Mr. Lu Xueyu processes more than 40 patents relating to the contents intelligence service algorithms. Mr. Lu has more than 13 years experiences in big data and AI industry, he has had an in-depth comprehension and long-term practice in big data, AI and personalized recommendation and Mr. Lu is one of the earliest practitioners in this field in China. Mr. Lu worked in Tencent, Alibaba Youku and Xiaomi and was responsible for the construction and management of big data and artificial intelligence teams, gained many successful implementation experiences for the establishment of big data and recommendation systems. In 2006 in Tencent, Mr. Lu took the lead in using artificial intelligence technology in virus discovery, effectively helped Tencent to protect nearly 1 billion QQ users’ account information security. In Youku, Mr. Lu served as technical director and set up the big data and personalized recommendation system for videos, the system was able to proceed more than 100 billion data daily, it was the system with the highest recommendation accuracy in the field of video websites at that time. During the time in Xiaomi, Mr. Lu was the technical director and was in charge of Xiaomi’s data workshop, he was also responsible for the Xiaomi ecological big data business.Marketing Technology News: RevJet Announces Results of Second Ad Experience Sentiment Report Revealing Change in Sentiment, Behavior of Online Consumers Luokung Technology Corp. Announces to Acquire Artificial Intelligence Company PRNewswireMay 14, 2019, 2:55 pmMay 14, 2019 AcquisitionAIBotBrain AI Technologycontent managementLuokung TechnologyMarketing Technology NewsNews Previous ArticleTechBytes with Adam Solomon, Chief Marketing Officer at LotameNext ArticleGoogle Selects Webpals Mobile to Join App Campaign Partner Programlast_img read more

first_imgUnstoppable Domains, a software company building domains on blockchains, today announced which 60 .zil domains it will auction on June 27. These domains represent the top 60 most watched Zilliqa domain names on the Unstoppable Domains website. The top domain, bitcoin.zil, has already attracted 505 potential buyers.“We are excited to see growing enthusiasm for blockchain domains,” said Matthew Gould, Unstoppable Domains CEO. “These domains provide two very critical benefits to users: they enable people to send crypto to a single human readable name, and they offer a platform to create uncensorable websites. The concepts of free speech and growing the crypto community are really resonating with our customer base.”Marketing Technology News: Triton Digital Integrates Centro’s Basis Platform with the a2x Programmatic Marketplace.Zil domains have seen high demand over the past 3 months, even though top domains have yet to be released. Users can, however, watchlist the domains they are most interested in bidding on during the coming public auction. Here are the top 60 most watchlisted domains:Which domains will be up for auction?1. bitcoin2. crypto3. porn4. blockchain5. money6. insurance7. gold8. cars9. hotels10. satoshi11. bra12. zil13. usa14. bank15. wallet16. beer17. ethereum18. carinsurance19. lasvegas20. pay21. trump22. weed23. travel24. toys25. pizza26. cannabis27. xxx28. litecoin29. privatejet30. music31. xrp32. fb33. z34. shop35. 36036. coffee37. coin38. cash39. vacationrentals40. porno41. hotel42. payme43. booking44. diamond45. insure46. game47. exchange48. 149. ripple50. donaldtrump51. abc52. cardano53. auction54. shoes55. ai56. car57. we58. domain59. elonmusk60. israelThe auction will be split into two phases. During phase I, the 60 most watchlisted domains will be available for a buy now price of $10,000 each. Domains can be purchased using bitcoin, ethereum, litecoin, and bitcoin cash.Marketing Technology News: Mindtree to Showcase Contextual, Real-Time Solutions for Personalized Traveler Experiences at HITEC MinneapolisDuring phase II, domains can only be purchased with Zilliqa.Bidding will start between $10 and $1,000 depending on the price of the domain in the pre-order phase. Each subsequent bid must be at least 5 percent greater than the previous bid. If a person is outbid, they will immediately get their funds returned. New bids will add additional time (~1 hour) to the auction to prevent auction sniping. Also, bidding will be capped at $10,000 per domain. Anyone in the world can participate and anyone in the world can watch the auctions as they happen.Marketing Technology News: CoreMedia Announces CoreMedia Content Cloud – Marketing Connector on Salesforce AppExchange, the World’s Leading Enterprise Cloud Marketplace Marketing TechnologyMatthew GouldNewsUnstoppable DomainsZilliqa Domain Previous ArticleMarTech Interview with Duncan Stockdill, Co-Founder and CEO at CapsuleNext ArticleFranklin Sports Selects CommerceIQ To Empower Their E-Commerce Team To Manage Amazon Holistically Unstoppable Domains Announces the Top 60 Zilliqa Domain Names Up for Auction Business WireJune 19, 2019, 1:45 pmJune 19, 2019 last_img read more

first_imgAnsweriQ’s Robo Assist Enables Freshly to Reduce Customer Service Response Times by 90% Utilizing Artificial Intelligence (AI) and Robotic Process Automation (RPA) AnsweriQ, a leading provider of intelligent automation for customer service, announced the availability of its product, Robo Assist, which enables single-click automation for agents – a new offering that uses AI and RPA to resolve cases. Single-click automation empowers the agent to automate mundane and repetitive scenarios like refund processing, account management, service upgrade, invoice reconciliation, inventory lookup, and many more.Freshly, a wellness company that delivers fully-prepared, healthier meals to customers weekly, has partnered with AnsweriQ to improve its customer service efficiency and experience. Freshly’s mission is to modernize healthy eating by providing freshly made, nutritious meals that don’t require cooking, cleaning, or a lot of time.Marketing Technology News: Top of Mind Networks Adds BombBomb Integration to Surefire CRMFreshly’s rapid growth after national expansion this year requires the team to continually focus on implementing solutions that give their customers immediacy, responsiveness, and consistent service across all channels. This is key to scaling Freshly’s customer service while maintaining a good user experience. Freshly has recently deployed AnsweriQ’s Robo Assist to scale their customer service and improve their customer experience while driving efficiencies.“We are seeing significant growth in Freshly’s direct-to-consumer business as we expand to different types of customers and expand our hours of operation and our contact channels. So for us, the challenge is maintaining the gold standards of customer service, tight response times, and high CSAT as we grow. AnsweriQ’s Robo Assist using AI & RPA fully automates our customer service order cancellation process. What used to take five to seven minutes of an agent’s time now takes us less than 30 seconds with single-click automation. It integrates seamlessly with Zendesk, our CRM platform, and works across all of our channels whether a customer emails, chats or calls us,” said Colin Crowley, VP of Customer Experience at Freshly.Marketing Technology News: Yext Study: 58% Of Healthcare and Pharmaceutical Marketers Say Their Marketing Management Strategy Needs Major ImprovementsSince implementing AnsweriQ’s Robo Assist, Freshly has seen a 90% reduction in handle time and an 11x improvement in agent productivity. Further, this allows Freshly’s customer service team to address and resolve time-sensitive requests from customers and also handle spikes.“Like Freshly, leading subscription services like Dollar Shave Club, BarkBox and StitchFix offer increased personalization, and ease of use via an automated experience. For these businesses, you cannot separate the customer experience from the product. AnsweriQ’s AI-based intelligent automation provides speed, increased solve rates for customer service, lower-cost, consistency and improved customer experience. The power of AnsweriQ’s AI along with RPA delivers single-click automation that takes a critical next step in enabling us to fully automate the handling of customer service,” said Pradeep Rathinam, Founder and CEO of AnsweriQ.Marketing Technology News: PMG Launches Marketing Intelligence Platform — Meet Alli AnsweriQ Unveils New Single-Click Automation for Customer Service Teams Business WireJune 26, 2019, 3:48 pmJune 26, 2019 AIAnsweriQNewsRobo AssistRPASingle-Click Automation Previous ArticleSDL Wins AI Breakthrough Award for Best Machine Translation SolutionNext ArticleNetLine Launches a No-Cost Tool to Access B2B Content Consumption Datalast_img read more

first_img crmdigital marketing solutionsiFOLIOMAX MarketingNewsSales and marketing Previous ArticleMobify Report Delivers First Ecommerce Benchmarks for Progressive Web AppsNext ArticleIt’s Ok to Message Your Customers – but They’re Not Your Friends iFOLIO Honored with Global Excellence Award, Best in Personalized Digital Marketing Solutions – 2019 by AI Global Media PRNewswire2 hours agoJuly 23, 2019 Deliver delightful Customer Experiences In today’s digital world, buyers are more informed and have high expectations when they interact with a company.  It’s critical for enterprises to maximize that customer touchpoint with an experience that feels custom and differentiated.iFOLIO is recognized with the Global Excellence Award “Best in Personalized Digital Marketing Solutions – 2019” by AI Global Media for innovation, growth, and delivering results through an enterprise digital portfolio platform. Digital portfolios are effective marketing because they are personalized, private, and delivered 1-to-1.  iFOLIOs have images, videos, and animated charts and are shared via SMS, email, and any way you share a link.  The private portfolios generate open rates up to 75% from mobile share, and engagement up to 2 min 40+ seconds in a market where attention spans average 7 seconds.Marketing Technology News: Gartner Survey Shows Inside Sales Organizations Risk Losing 24% of Employees This YearThrough iFOLIO, companies can engage their customers and prospects more authentically, optimizing the relationship, and delivering a remarkable experience. iFOLIO platform enables sales or account management to deliver a portfolio directly to a customer via SMS or email and then follow-up from the sales dashboard. The iFOLIO Analytics enable more thoughtful, data-driven follow-ups and Reverse CRM™ automates outreach notes into the CRM system reducing reporting workloads.Growth is in the iFOLIO DNA. Using its own incredibly effective platform for sales and marketing, iFOLIO grew paid customers 1100% last year.Marketing Technology News: Airbnb Introduces New Search Capabilities for Business TripsToday iFOLIO powers over 3500 clients in 58 countries including the Atlanta Falcons NFL, Equifax, iD Tech and was honored with a 2019 MAX Marketing Innovation Award by the Atlanta Business Chronicle for introducing a new standard of digital engagement for enterprise professionals with a platform for private portfolio sites for customer introductions, presentations, and proposals.“We are so honored to accept this award and to serve our incredible clients as they transform their customer experience with personalized portfolios and SMS.  We believe relationships are central to business and the future of incredible presentations, stories, and customer experiences are private digital portfolios,” says Jean Marie Richardson, Founder and CEO of iFOLIO.Marketing Technology News: Adobe Survey Says That Voice and Screen Combined Are the Futurelast_img read more

first_img Content SyndicationMarketing Technology NewsNewsPaul SalaySyndigoWiseBase Previous ArticleBlueJeans Gateway for Microsoft Teams: Promotion for Free Cloud Interop LicensesNext ArticleYandex.Taxi Expands into the Regions Syndigo Acquires European Content Provider WiseBase PRNewswireJuly 15, 2019, 7:00 pmJuly 15, 2019 Leading Database and Technology Company Provides Product Content Management Solutions in EuropeSyndigo, a Chicago-based leading provider of verified product content syndication services, and a portfolio company of The Jordan Company (“TJC”), announced the acquisition of WiseBase, an innovative product content and technology company with clients across Europe. The move strengthens Syndigo’s global footprint, providing clients with broader access to retailer networks, in-country client service expertise, and a further expanded library of digital product content.Marketing Technology News: JumpCrew Announces Inaugural Conference “JumpCon: The Digital Sales Transformation Summit”“Many of our clients are global enterprises with aspirations for further geographic reach,” said Syndigo CEO Paul Salay. “With this strategic acquisition, we are strengthening our coverage in Europe to provide added value to our clients, delivering accurate and verified product information across the consumer, retail and eCommerce industries in a single, integrated platform.”“There is a need for localized solutions specific to each market, and we want to provide the best coverage and service for our clients in Europe,” said Aleksander Krzyżowski, General Manager, Syndigo Europe. “The acquisition of WiseBase provides Syndigo with the opportunity to extend its industry-leading reach and footprint and to deliver more consistent and engaging experiences for shoppers across Europe. We are excited to welcome WiseBase to the Syndigo family.”Marketing Technology News: Inpixon to Acquire Indoor Mapping Leader JibestreamWiseBase provides retailers with a complete ecosystem to facilitate the exchange of verified and enhanced product information. Currently, WiseBase works with leading retailers in Poland, Romania, and Germany with the technical capabilities to expand into other European geographies. WiseBase has invested significantly in developing technology that provides brands with the ability to manage and syndicate product information to their retail partners, while also serving as the brand’s central product database.As a global provider of core and enhanced product content, Syndigo delivers innovative solutions to retailer and brand clients through its integrated Content Experience Hub (CXH) platform. The acquisition and integration of WiseBase’s technology and network of retailers and brands will provide incremental value to all market participants.“It has been our mission to minimize the time spent preparing and sending product descriptions between brands and retailers,” said Piotr Morkowski, Managing Partner at WiseBase. “We are excited to join our new global partners at Syndigo, who share our commitment to supporting brands both locally and globally.”Marketing Technology News: Study Finds Enterprises Rapidly Shifting to Hybrid, Multi-Cloud Business Modellast_img read more

first_imgIt seems we may soon get a new Fantastic Four movie! According to reports by Greek WorldWide, with the rights to Fantastic Four back in Marvel’s hands, they may have already started planning how to introduce the first Marvel comic creation.According to rumours, Marvel Studios is aiming for 2022 release for the ‘Fantastic Four’ reboot and GWW cites sources that say that ‘Ant-Man’ director Peyton Reed could be directing the new film. GWW further says that Reed has already pitched his vision of Fantastic Four multiple times and his pitch includes a 1960s setting that involves the Quantum Realm, and possibly The Black Knight.According to GWW, Reed has said, “Visually, one of the things we always talked about – and this was 2003 – was The Fantastic Four as daytime superheroes. They don’t have secret identities. They’re very much a part of the fabric of Manhattan. In that universe, if you go to New York to the Empire State Building or the Statue of Liberty or the Baxter Building, it was all a part of that. We talked about it being a ’60s period movie, but Fox at the time was not into it.”For the unversed in Marvel Cinematic Universe, The Fantastic Four were first created by Stan Lee and followed the adventures of Mr Fantastic who had the ability to stretch his body in any way he desired, Invisible Woman who disappear when desired and generate force fields, Human Torch who could turn into flames and The Thing, a man who is entirely made of rock and has superhuman strength.Most fans think of the 2005 Tim Story directorial, starring Chris Evans, Jessica Alba, Ioan Gruffudd and Michale Chiklis as the first outing of the Fantastic Four, however, it is the unreleased 1984 film by Oley Sassone, that first showed the four with superhuman abilities. Chris EvansFantastic Fourfantastic four peyton reedMarvel Comics First Published: June 7, 2019, 1:08 PM ISTlast_img read more

first_img In another tweet, Slott also suggested that provided Reeves is worthy of playing Moon Knight as per him, he could also pull off the roles of Mercenary, Marc Spector; Cabbie, Jake Lockley and Millionaire, Steven Grant with ease. Always Be My MaybecabbieDan SlottJake Lockley First Published: June 21, 2019, 5:46 PM IST Whoever plays Moon Knight has to also be able to pull off:Mercenary, Marc Spector.Cabbie, Jake Lockley.And Millionaire, Steven Grant.That’s your man for the job.— Dan Slott (@DanSlott) June 20, 2019It is also being speculated that Reeves has been approached to play a part alongside Angelina Jolie in Marvel’s The Eternals. Created by Jack Kirby in 1976, the story of The Eternals is set millions of years ago when the cosmic beings — known as the Celestials — genetically experimented on humans to create super-powered individuals — known as the Eternals — along with the villainous Deviants. However, nothings stands confirmed at this point in time.Reeves is currently working on the sequel to his 1989 film Bill & Ted’s Excellent Adventure, which is titled Bill & Ted Face the Music. The announcement of the sequel was made in June this year, while the official release date is not yet announced.Follow @News18Movies for morecenter_img If Keanu Reeves’ popularity on social media and film business was lagging behind in any respect post the release of John Wick: Parabellum and his much loved cameo in Netflix film Always Be My Maybe, it sure received a major boost when Kevin Feige, President of Marvel Studios, admitted that Reeves was indeed eyed for the superhero franchise almost every time a film was made. Soon after Feige’s statement started circulating, fans of The Matrix star could not help but wonder which part would suit his humble personality the best.In the matter, Dan Slott, Amazing Spider-Man writer and current Fantastic Four scribe, recently offered his suggestion as to which comic book character would Reeves look best in. Slott wrote on Twitter, “I’m seeing lots of people saying Reed Richards, Adam Warlock, and Silver Surfer. My vote? Marc Spector: Moon Knight. For those who are wondering who Spector is, cbr.com reported that Moon Knight is a schizophrenic follower of the Egyptian moon god, Khonshu, who captivated fans with his multifaceted personalities, violent methods and unpredictability. See Slott’s tweet here: I’m seeing lots of people saying Reed Richards, Adam Warlock, and Silver Surfer.My vote?Marc Spector: Moon Knight https://t.co/TOpqZnA80o— Dan Slott (@DanSlott) June 20, 2019last_img read more

first_imgShahid Kapoor and his wife Mira recently celebrated their fourth wedding anniversary on July 7. The adorable duo has already welcomed two munchkins in their life, Misha and Zain, and has been setting up family goals ever since. While both the love birds keep sharing pictures with their little family every now and then, Mira is taking the mother-daughter combo to another level by posting a twinning picture with daughter Misha.On July 8, Mira took to Instagram to share a throwback picture with her baby girl, where both the lovely girls were donning the matching-colour outfit. With a green kurta and a pink dupatta, the lovelies looked adorable as they smiled for a selfie. Mira shared the picture on Instagram with the caption, “Match #tb.” Recently, Shahid and Mira celebrated their fourth anniversary and poured in some love for each other through Instagram posts. While Shahid posted a picture of Mira, writing, “Her first picture I saved on my phone. And now almost every second picture has her in it. She is #life. I love you @mira.kapoor thank you for being you,” Mira shared a picture from their wedding, with a caption, “You make my world and me go round #happy4.” On the professional front, Shahid has been recently been in news for his latest movie Kabir Singh. The film, despite being attracted by controversies, managed to earn around Rs 225 crore, and has become one of the highest grosser of the year. The movie also starred Kiara Advani and is the Hindi remake of the Telugu movie Arjun Reddy.Follow @News18Movies for more center_img arjun reddyKAbir Singhkiara advaniMira Kapoor First Published: July 9, 2019, 11:21 AM ISTlast_img read more

first_imgNew Delhi: External Affairs Minister S Jaishankar on Sunday responded to tweets by several Indians abroad seeking help, signalling continuation of his predecessor Sushma Swaraj’s social media outreach in assisting people in distress.Swaraj leaves a legacy of an easily accessible External Affairs Minister who helped the diaspora in distress through Twitter. In a series of tweets, Jaishankar responded to calls for help by several Indians abroad, assuring them that Indian missions in respective countries were trying to address their issues.When one Mahalakshmi tweeted seeking help to her family members whose passports were lost in Italy during a trip, Jaishankar said, “Our Embassy in Rome/ Consul General in Munich will extend all assistance. Please be in touch with them @IndiainItaly @cgmunich.”Our Embassy in Rome/ Consul General in Munich will extend all assistance. Please be in touch with them @IndiainItaly @cgmunich https://t.co/JDGEfdZ5pP— Dr. S. Jaishankar (@DrSJaishankar) 2 June 2019The new external affairs minister also responded to a Twitter user’s request for help in finding her husband in Kuwait and bringing him to India. She said her husband was not responding to court summons and living peacefully in Kuwait.To this, Jaishankar tweeted: “Our Embassy in Kuwait is already working on it. Please be in touch with them @indembkwt.”Our Embassy in Kuwait is already working on it. Please be in touch with them @indembkwt https://t.co/w9BRPXTTZr— Dr. S. Jaishankar (@DrSJaishankar) 2 June 2019Our Embassy in Oman is trying to resolve this. Please continue to stay in touch with them @IndEmb_Muscat https://t.co/qnUAoRgt2m— Dr. S. Jaishankar (@DrSJaishankar) 2 June 2019Responding to another on national education policy, he said it was a only a draft report and that no language will be imposed. “The National Education Policy as submitted to the Minister HRD is only a draft report. Feedback shall be obtained from general public. State Governments will be consulted. Only after this the draft report will be finalised. GoI respects all languages. No language will be imposed,” he said.As the draft education policy recommends introduction of Hindi from pre-school, there have been voices of opposition, especially from Tamil Nadu, to the recommendation.In his first official Twitter post, Jaishankar on Saturday said he was “proud to follow on the footsteps” of Swaraj.”My first tweet. Thank you all for the best wishes! Honoured to be given this responsibility. Proud to follow on the footsteps of @SushmaSwaraj ji,” he said.In a surprise move, Prime Minister Narendra Modi picked the seasoned diplomat to helm the key ministry, nearly 16 months after he retired as foreign secretary.Jaishankar served as foreign secretary from January 2015 to January 2018 and both he and Swaraj, the external affairs minister in the previous government, were credited for bringing vibrancy in India’s foreign policy.Jaishankar’s appointment is seen as Modi’s attempt to add further strategic heft to India’s external engagement.”We at Team @MEAIndia continue to be at your service 24×7. Happy to be leading the effort with my colleague MoS Muraleedharan ji @VMBJP,” Jaishankar said in another tweet on Saturday.As external affairs minister in the previous government, Swaraj was known for prompt response on Twitter in addressing grievances of overseas Indians.Her interaction with the diaspora through social media, established her as someone who can be reached in distress with just the click of a mouse. embassyExternal Affairs ministerNarendra ModiNational Education Policy First Published: June 2, 2019, 8:21 PM ISTlast_img read more

first_imgStory TimelineHow to install iOS 13, iPadOS & macOS Catalina – and why you should waitiOS 13 beta 3 now available: Here’s what’s newEpic tells Fortnite players to hold off on iOS 13 beta for now This update will come with a new icon for voice messages in the Messages app. So make sure when you download and load the software, you head into Messages to make certain you’re recognizing the new icon – and not just assuming that Voice Messages are gone completely. This update will bring a few more updates in the visual space just like that – so keep your wits about you!There’s a new Rearrange Apps button that’ll appear when you activate the function. The way you’ll do this is the same as it ever was: Rearrange Apps by long-pressing any one app on your home screen. You’ll find a new button that’ll ask if you wish to actually rearrange apps or not.If you’re using the iPad version of this software, you’ll find a blinking line showing which side of your split-screen is receiving attention – specifically with text. You’ll also find a new pill-shaped indicator of which side of the split-screen you’re inputting on currently.If you’re in the beta and head into Settings, Health, Headphone Audio Levels, you’ll see a new set of explanations for what’s going on in the latest Beta in this specific area. Perhaps strangest of all, you’ll find the FaceTime Attention Correction feature in play. This is the not-at-all-creepy feature that’ll change the direction of your eyes when you’re speaking in FaceTime, so it looks like you’re looking right at the person to whom you are speaking. When’s the last time you had your eyes redirected automatically? To attain this update, you’ll need to head into the iOS Public Beta page at Apple and tap forth! If you’ve already done this, simply head into your Settings and get yourself the latest Software Update. It SHOULD be the iOS 13 Beta 3 to which we’ve been referring – if not, just wait a bit longer! Today the folks at Apple made final the iOS 13 BETA release for the public, allowing pretty much anyone to take a peek on their own iPhone. This means users of the iPhone XS, iPhone XS Max, XR, 8, 8 Plus, 7, 7 Plus, 6s, and 6s Plus will be able to download the software immediately, if they do so dare. There’s also a new iPadOS 13 (iOS 13 for the iPad, that is to say) out and available right now, too – in Beta form. last_img read more

first_imgReviews are pretty mixed, and so are the phone’s specs. Even by late 2016’s standards, the Kodak Ektra is a bit dated as far as smartphones go. The MediaTek Helio X20 running inside is hardly the latest and is matched with only 3 GB of RAM. The 5-inch display, though handy, reaches only 1920×1080 pixels. While good enough for most, that does mean that you won’t be seeing the photos and videos you just captured in all their glory. Kodak is a name you would immediately associate with cameras but with this generation’s obsession with smartphone, it couldn’t but help dip its toes into that market as well. That product is the Kodak Ektra which is finally making its way to the US. But with nearly half a year’s time since it was first announced, the Ektra faces a very tough battle against the market’s top contenders for the best smartphone camera. The camera sounds great, at least on paper. It has a 21 megapixel fast focus sensor, an F/2.0 lens, phase detect autofocus, optical image stabilization, and dual LED flash. That said, early reviews of that camera seem to hint that the hardware is hampered by a mediocre camera app, despite offering the bells and whistles of an “advanced” manual mode.One thing going for the Kodak Ektra is its design. At least if you go for that look. It definitely looks like a digital camera first and a smartphone second, including a protruding grip that photographers are comfortable with. Kodak is even making available leather cases that are designed for cameras rather than phones, including a pink one from fashion designers Pop & Suki.center_img The Kodak Ektra smartphone will at least be priced accordingly, selling for only $399, unlocked and SIM free. That’s quite a drop from its initial $549 price tag. It is, however, going up against the likes of the HTC U11, the Google Pixel, and the Samsung Galaxy S8, all of whom occupy top spots in DxOMark’s famous list.last_img read more

first_imgThe device goes by the name Samsun Gear Sport, and it would seem to be a fairly decent bet that it’s coming with rugged intentions. The backside image we’ve got below comes from the FCC VIA TL, showing where regulatory labels will be located. In this image we can see a device that’s nearly identical to the Samsung Gear S3 – save some small differences.One rather noticeable difference is the appearance of the name SAMSUNG GEAR SPORT. This should be a FAIR indicator of the name of the device as it heads to the production floor. Also present in the report is a note about Bluetooth Low Energy certification issuance. This certification was issued all the way back on August 7th (that’s just this week.)The original Samsung Gear S3 was revealed back in August of 2016. That MIGHT mean that Samsung is now on a two-year-refresh cycle for their most major wearable device. Instead of releasing some sort of “slightly better” version every other year, the Sport watch may come into play. Story TimelineiPhone 8 and Galaxy Note 8 aren’t playing the same gameGalaxy Note 8 launch date has been tippedGalaxy Note 8 may come with a welcome surpriseGalaxy Note 8 release day 3D-touch tippedGalaxy Note 8 stock wallpapers leak: see and download them here The next Samsung event is all but guaranteed to be home to the Galaxy Note 8 – but that’s not all. Today we’ve got word that the next Samsung wearable device – a perfect companion for the Galaxy Note 8, as it were – just passed through the FCC. This comes not long after the same device passed Bluetooth certification, meaning – or at least indicating – that it’s right on the verge of being revealed by Samsung in full.center_img Above you’ll see our original Samsung Gear S3 hands-on video as recorded a bit less than a year ago. The event in which this device was first revealed took place during IFA 2016. This year IFA 2017 is scheduled for a similar span of days, and Samsung’s event for the Galaxy Note 8 – and likely this Sport watch – is set for August 23rd. We’ll be there LIVE in effect!last_img read more

first_imgHMD Global has a pretty gosh-darned good track record of bringing updates to Android devices – especially lately. HDM Global phones of all sorts have been getting Security Updates lately, at least. Security Updates are the most essential updates to Android devices – followed closely by full OS updates for new and tweaked features.The KEY here will be timing. If HMD Global can stick to updates – and make that a big priority once their first wave of Nokia phones proliferate the earth – they’ll make a Motorola-like impact. Back when the first Moto X and Moto G were first released, the then-Google-owned Motorola had updates REAL quick.Android Oreo will quite likely come to Nokia 3, Nokia 5, Nokia 6, and Nokia 8. Cross your fingers HMD Global keeps Sarvikas’ promise! According to Nokia dot com, Nokia and/or HMD Global promises “You get an experience that’s focused and clutter-free, and we’ll make sure you keep getting regular updates, so you’ll always stay on top of features and security.” In an interview with NDTV, Sarvikas promised each of these phones would get two years of Android updates. The article includes this promise twice, but does not write the exact words used by Sarvikas for the two-year update promise.I’d believe in the two-year promise only if the smartphone included that promise in writing at the point of purchase. If updates are important to you – beyond security updates, that is – be sure to get that promise when you buy.Those users that are already on the update list and want to update to Android 8.0, head over to our How to download the Android 8.0 Oreo update now guide. It’s quite simple, really – mostly just heading to Settings – System – System updates. Otherwise head to Google Developers to see if the device list miraculously contains a Nokia phone – likely it still just contains Nexus and Pixel devices as such. Android Oreo was announced to be coming to all current-age Nokia smartphones over the weekend. The timing of these updates is not yet known, but Juho Sarvikas, Chief Product Officer for HMD Global seems to believe that the company is ready and capable of bringing the newest version of Oreo to all new Nokia phones. HMD Global is the company that currently licenses the Nokia brand name to create smartphones with what remains of the original Nokia company. Story TimelineAs Nokia 8 nears, HMD’s veteran CEO suddenly departsNew Nokia 3310 torture test: see how it faresNokia 8 prototype says hello in leaked imagesNokia 8 Copper Gold model leakedNokia 2 entry level Android phone is apparently realNokia 8 release specs just droppedNokia 8 Bothies aren’t the camera gimmick we wantedNokia 8 might not launch in US or Chinalast_img read more

first_imgWhat’s this third device I speak of today? It’s a magician – a sort of device that existed in earlier tests of the latest version of Android, then disappeared for a while. It’s re-appeared in the same testing bin that the other two Pixel 2 devices first appeared – AOSP. There, we see the re-appearance of Muskie.SEE TOO: Pixel 2 XL LG-made screen saga keeps getting worseThis third Pixel device is not confirmed by Google, nor HTC, or anything like that. Instead, we’re looking at codes dug up by XDA which show the device as HTC-made, “manufacturer” Google, with a massive battery inside. This device would be the beast of the group, carrying with it a battery that’s 3830 mAh large. That’s bigger than the Google Pixel 2 XL, a device with a 3520 mAh battery inside.What’s more, this device has the same dots per inch as the larger Pixel released this year. That would seem to indicate that it’s a device with a very, very similar build – if not the same display with a different body. That’s very interesting – very interesting indeed.As this device is lumped in with codes for Walleye and Taimen – both previously released Pixel devices. Over at Droid Life today, they’ve got a tip on the next generation of Pixel devices, too – Albacore and Blueline. If that’s true, why would Google still be working on Muskie?Is it a half-step device with a larger battery made to be released halfway between this year’s Pixels and the Pixels of 2018? Or is this some sort of magical third category? Maybe a beast of a phone running Android One?Have a peek at the timeline below to see what other recent Google-made oddities have popped up. And stay tuned as we continue to unravel this fishy mystery! Story TimelinePixel 2 XL, iPhone 8 Plus drop tests push glass to the limitsPixel 2 XL screen saga keeps getting worsePixel 2, 2 XL has some audio issues, here’s a temporary fixPixel 2 teardown shows unusual waterproofing methodPixel 2 unit fails quality control, still shipped to buyerGoogle Lens app download out for Pixel and rooted Android It would seem fitting that this week another HTC-made Pixel 2 XL device would be found. This, a week in which the LG-made Google Pixel 2 XL (already out in the wild – see link below) is the subject of display-based controversy. This, a week in which the HTC-made Pixel 2 has had few to no negative reports – just the opposite – the smaller device has everything the larger one does, with a smaller display whose colors and viewing angles are all on-point.last_img read more

first_imgSamsung’s test involved a 5G router and a 5G Radio, plus a virtualized core and virtualized RAN. The test happened on a train running between two stations that were about 1 mile apart from each other. The on-board 5G router was used to download an 8K video and to upload a 4K video sourced from a camera mounted on the train. KDDI is eyeing 5G tech as a way to revolutionize trains.Talking about this, KDDI’s Senior Managing Executive Officer Yoshiaki Uchida said, “With 5G expected to bring railway services to a whole new dimension, the success of today’s demonstration in everyday locations such as a train and train station is an important milestone indicating 5G commercialization is near.” KDDI plans to launch 5G by 2020; it opens the doors to many potential benefits, such as better on-board WiFi and a better infotainment experience on the trains. For its part, Samsung has been putting ample effort into developing and testing 5G technologies. A recent report claimed that Samsung has been working with the U.S. military to develop and test a 5G network prototype. The technology is reportedly of interest to the military as a way to supply units with high-speed and relatively portable Internet connectivity while out in the field. SOURCE: Samsung News Samsung recently tested 5G on a train traveling at about 62MPH and was able to hit a peak speed of 1.7Gbps. The company called its test, which was performed with Japan’s KDDI, a success, saying it achieved successful downlink and uplink handover in addition to the crazy peak speed. The test took place in Saitama, Japan, on October 17 through October 19.last_img read more

first_imgThe FCC has granted SpaceX’s application to use satellites for providing Internet service to regions around the world. According to the FCC, this is the first approval for a “US-licensed satellite constellation” that will use low-Earth orbit satellites to offer “broadband services.” The system may contain more than 4,000 satellites, and was confirmed by SpaceX back in May 2017. READ: This is SpaceX’s plan to beam internet to the whole worldThe FCC wants to provide all regions of the US with broadband Internet service, which means hitting speeds of at least 25Mbps. SpaceX may help hit that goal with its satellite-based plan, which would use satellites to beam high-speed Internet to the United States and other countries all over the world. According to the approval letter published by the FCC today, the system was proposed to contain 4,425 satellites.The Internet service won’t be free, so don’t get your hopes up. However, such a system could provide an unprecedented level of Internet access to places that historically have had poor service options. Many rural regions in the US only have access to dial-up or DSL, and some people are forced to depend on aging cellular networks or low-quality satellite services to get Internet access.AdChoices广告Of course, the system would also cover other places around the world that have a lack — or complete absence — of adequate Internet service. Before offering its network, though, SpaceX had to get approval to send the satellites up, and that’s where the FCC’s authorization comes in. The Commission has previously approved similar requests from Telesat, OneWeb, and Space Norway.The FCC hints that it has outstanding requests from other companies with similar plans, too. “These approvals are the first of their kind for a new generation of large, nongeostationary satellite orbit, fixed-satellite service systems,” the agency says, “and the Commission continues to process other, similar requests.”SOURCE: FCClast_img read more

first_imgMicrosoft suggests they’ve brought the original Surface Hub to more than 5000 customers across 25 markets. “Over half of Fortune 100 companies have purchased Surface Hubs to improve team’s efficiency and how they collaborate,” said Chief Product Officer at Microsoft, Panos Panay, “breaking down barriers and creating real business value.”This device has the same 2:3 aspect ratio as other Surface products. So it’ll look and act like one massive Surface tablet. Even if you’re an individual with no real use for such a massive tablet – you might just find yourself wanting one. Good luck to you in finding one to buy.Businesses and other “select commercial customers” will be able to purchase this device in the year 2019. This monster will be tested by select commercial customers starting this year. Release pricing is not yet available – but if it costs anything like the first Surface Hub, everyday individuals will probably want to go ahead and pass. This machine is made to make the most of software like Microsoft Whiteboard, Microsoft Teams, and Office 365. In addition to working on its own, this big computer can be tiled together with up to 4 screens at once, relatively seamlessly. Microsoft’s releasing this device with its own Steelcase-made accessories like a rolling stand and mounts for walls.Under the hood is a 4K camera that’s able to rotate with the device. Integrated speakers make this as all-in-one a device as you could ask for at this size. Far field mic arrays make it so everyone in the room can be heard when there’s a video call. Businesses in need of wall-based Windows 10 devices rejoice, there’s a new Surface Hub 2 in town. This device brings out the best bits of the Surface Hub 1 and advances all the parts that needed advancing. This beast features a 4K+ 50.5” multi-touch display and it’s made to get business done.last_img read more

first_imgThe cars are based on GM’s regular Bolt EV. That’s an all-electric hatchback, with 238 miles of EPA-certified range. For autonomous purposes, the car is customized with LIDAR laser rangefinders, extra cameras and other sensors, and new processing power to crunch all the data in real-time. Cars have been in testing – in association with Cruise Automation, the self-driving startup GM acquired – in San Francisco, CA; Scottsdale, AZ; and Detroit, MI. Trials on public roads began in June 2016. GM has also cut a deal with ride-sharing firm Lyft to work on the technology together, with the eventual goal of deploying autonomous cabs out into public service. What’s really important, though, is not just what the autonomous Bolt EV are being built with, but how they’re being built. GM was the first automaker to assemble its self-driving prototypes at a mass-production facility, rather than in a more boutique operation as might commonly be the case for small-run vehicles. That takes place at the Orion Township plant, which started the next-generation production run in January 2017. While the numbers involved may still be small today, it’s part of GM’s vision for shifting autonomous vehicles into the mainstream down the road. “To achieve what we want from self-driving cars, we must deploy them at scale,” Kyle Vogt, CEO of Cruise Automation, said of the milestone. “By developing the next-generation self-driving platform in San Francisco and manufacturing these cars in Michigan, we are creating the safest and most consistent conditions to bring our cars to the most challenging urban roads that we can find.”That’s still some way off, of course. However GM has also opted to accelerate availability of its regular Bolt EV. Though the car was always planned for a roll-out across all fifty states in the US, that was a staggered affair. Now, Steve Majors, marketing director for cars and crossovers at Chevrolet, told Automotive News, the timescales are being shortened. NOW READ: 2017 Chevrolet Bolt EV ReviewIn fact, nationwide orders for the Bolt EV began on June 1, he confirmed. Delivery across the US will be rolling out by August. Among the factors which enabled that was faster than expected installation of training and maintenance upgrades at dealerships, as well as the mandatory installation of DC fast-charging stations that Chevrolet required. 130 new autonomous Bolt EV test cars have rolled off GM’s production line, the automaker has announced today, each fitted with the new version of its self-driving hardware. The expanded Chevrolet fleet will join the 50+ current-gen autonomous Bolt EV cars which GM has already been using to refine its self-driving platform. They’re currently navigating the streets in three US states. Story TimelineChevrolet plans “thousands” of autonomous Bolt EV from 2018 say insidersGM begins expanding its autonomous Chevy Bolt fleet5 Things we learned on our Chevrolet Bolt winter road triplast_img read more

first_imgHere’s the new Galaxy Fit E render, extracted from the APK. Also, here are renders of the Galaxy Watch Active and Galaxy Buds, but you’ve already seen those before. pic.twitter.com/jU9tj1id29— Mishaal Rahman (@MishaalRahman) February 15, 2019 It is, however, the first time we’re seeing the Galaxy Fit, billed to be the Fitbit Charge 3’s new rival. Just like with the Galaxy Watch Active, Samsung has made a rather drastic design change, throwing away the curved screen for a flat one. We’ll have to see what else the wearable has in store and whether the new aesthetic will make it more appealing to buyers. AdChoices广告 It seems that Samsung is truly retiring the Gear brand, putting all its mobile products under a single “Galaxy” name, regardless of form or operating system. That has started with the Gear Watch, now Galaxy Watch, and the rumored Galaxy Buds that will succeed the Gear IconX. Now it seems that Samsung itself has accidentally confirmed that the Gear Fit trackers will also experience a change, but the new Galaxy Fit and Galaxy Fit e will bring more than just a new name.center_img Rumors of Samsung’s next fitness wearable started floating around last month when the name was spotted together with the Galaxy Buds. Given that thee latter is all but confirmed, it goes to reason that the Galaxy Fit is also real. Thanks to Samsung pushing some things to its Galaxy Wearable (formerly Samsung Gear) app, now we know how close all of those were to reality.The app shows the selection of new wearables you can add, including three that haven’t even been released yet. We’ve seen the Galaxy Watch Active, of course, and this image of the smartwatch confirms the lack of a bezel ring. There’s also the Galaxy Buds, coming in black and white colors. The app makes mention of a Galaxy Fit e model, which could be a more wallet-friendly version of the fitness tracker. If so, then there’s also a chance that Samsung has indeed adopted that naming convention and will call the Galaxy S10 Lite as the Galaxy S10e instead.last_img read more

first_imgQualcomm has won a legal case against Apple in the Southern District of California, the company announced. The case involved a lawsuit Qualcomm filed against Apple in July 2017 alleging the company had infringed upon some of its smartphone tech patents. A jury awarded Qualcomm $31 million in damages for three patents involving ‘popular smartphone features.’ The three patents at the heart of the legal battle include US Patent No. 8,838,949, 9,535,490, and 8,633,936. The patented technologies cover flashless booting, which enables a phone to connect to WiFi rapidly after being turned on, tech that enables phone apps to quickly get data to/from the Internet, and a method to get high mobile game performance and visuals while increasing battery life.The jury found that Apple infringed upon two of these patents with its iPhone 7, iPhone 7 Plus, iPhone 8 and 8 Plus, and the iPhone X. The latter three models were also found to infringe upon the third patent covered by the lawsuit, No. 8,633,936. Qualcomm’s executive VP and general counsel Don Rosenberg praised the ruling, saying:The technologies invented by Qualcomm and others are what made it possible for Apple to enter the market and become so successful so quickly. The three patents found to be infringed in this case represent just a small fraction of Qualcomm’s valuable portfolio of tens of thousands of patents. We are gratified that courts all over the world are rejecting Apple’s strategy of refusing to pay for the use of our IP.The $31 million in damages works out to $1.41 per iPhone found to infringe one or more of the three patents. That’s not a terribly burdensome figure for Apple, which tipped over the $1 trillion valuation milestone in 2018. However, this marks a solid score for Qualcomm, which is no stranger to legal tussles. Story TimelineQualcomm Quick Charge wireless power now works with Qi standardQualcomm just revealed the 5G chip to supercharge 2020Apple hits back at Spotify after antitrust complaintlast_img read more

first_imgToyota has announced the 2019 TRD Pro series trucks and SUVs. For 2019 the series will include the Tundra, 4Runner, and Tacoma. All the Pro models will feature Fox 2.5-inch Internal Bypass Shocks. The 2019 model trucks will be available this fall and each of the Pro vehicles will be offered in three colors including Super White, Midnight Black Metallic, and Voodoo Blue. SOURCE: Toyota That blue hue is a TRD Pro exclusive color found on no other Toyota trucks. Each of the vehicles gets Fox shocks tuned exactly for it at TRD. Toyota says that the design of the shocks allows for a plush ride on the roads but stiffens to prevent bottoming during hard use. The Tacoma TRD Pro uses shocks with 46mm piston and 8 bypass zones combined with springs that lift the front of the truck by an inch.That vehicle has Entune Premium JBL audio with a subwoofer and integrated NAV. Rigid Industries fog lights are included and the truck rides on 16-inch TRD Pro black wheels. A TRD Desert Air Intake is optional and helps reduce dust the truck might slurp up by moving the intake up by the windshield from the fender well. The Tundra TRD Pro uses Fox shocks and TRD springs for 2-inches of front lift. This truck has Rigid Industries fog lights, LED headlights, and LED accent lights. It rides on 18-inch BBS forged wheels and has special TRD touches on the interior. The 4Runner TRD Pro gets the same Fox shocks with a 1-inch lift out front. It can be fitted with the Premium JBL Audio system and gets several TRD touches on the inside.AdChoices广告The three vehicles all have the Toyota 36-month/36,000-mile warranty. All the models also have the Star Safety System with Vehicle Stability Control (VSC), Traction Control (TRAC), Anti-lock Brake System (ABS), Electronic Brake-force Distribution (EBD), Brake Assist (BA) and Smart Stop Technology (SST). Tundra and Tacoma also get, “Toyota Safety Sense P (TSS-P), which features Pre-Collision System with Pedestrian Detection (PCS w/PD), Lane Departure Alert (LDA) with Sway Warning System (SWS), Automatic High Beams (AHB) and high-speed Dynamic Radar Cruise Control (DRCC).last_img read more

first_imgBicycle rides recorded in Strava will not, from this point forward, be reported to Relive. Not through the group’s official API, anyway. If Relive wants to gain access to Strava data from now on, they’ll need to get extra creative. Before now, users would be able to quite easily create an automatically-compiled piece of media based in Relive using their Strava data, GPS, and photos taken during said trip. The final product was both interesting and highly share-friendly. We live in a socially networked in a highly addicted fashion sort of world, after all.Work was done between the two to fix whatever problems Strava had with how Relive handled user data. Strava said in a statement that “The current version of Relive violates several of the terms that we ask of API partners,” and that “We’ve worked hard with Relive to try to fix this, but they have ultimately chosen not to make the changes needed to honor their agreement.”AdChoices广告The statement from Relive posted a very detailed bit of documentation this week, making the case that it feels like they’re taking crazy pills because this relationship is just bananas. “After launching our first social features, we received a very unexpected message threatening to pull the plug. Given our long-term partnership, we immediately rolled back the changes like they requested,” said a Relive representative. After working with the company for over three years, Relive suggested that Strava seems to have had a major change of heart about a great many things. Maybe some lawyers jump into the party? “We then tried to call, email, and talk this out with Strava,” said Relive. “No response, except for new ultimatums and threats about our existing features they’ve applauded for years.”Bummer, for all those involved on the biking end. Users of Relive can still use the service, even without Strava – if they head to the upload page on their desktop or just record their activities straight through the Relive app. They can also continue to use devices from brands like Garmin, Suunto, Polar, or any other partnered group. UPDATE: Relive works with the following tracker apps: Runtastic, MapMyRun, MapMyWalk, MapMyRide, MapMyHike, Endomondo, Garmin Connect, Suunto, Apple Health (Watch) and Polar Flow account. Both Strava and Relive have made statements on their recent breakup, suggesting that the other was the one that was at fault. According to Relive, they worked with Strava and followed Strava’s recent takedown request – but were blocked from the API nonetheless. Strava said Relive was simply abusing its API. Story TimelineStrava fitness app arrives for Apple Watch Series 2Strava fitness tracking app reveals location of military basesFitness tracker Strava reveals names, locations, heart rateslast_img read more

first_imgMechanical endpoint range for pan axis control is 360° continuous rotation. Mechanical endpoint range for tilt axis control is between -95° and +220°, and roll axis control is -202.5° to +112.5°. Controlled rotation range for pan axis control is the same as mechanical endpoint range, while tilt axis is down to -90° to 145°. Controlled rotation range for roll axis control is plus or minus 30°.The battery inside this gimbal has a capacity of 2450mAh. That COULD be a very good thing – depending on how good this machine manages power. We’ll only know for sure once we get one in for review! DJI says the battery can last for up to 11 hours, which seems pretty incredible! This machine can be attained from DJI online for approximately $440 USD on its own. There’s also a “pro combo” that adds an rss splitter, screw, focus gear strip, focus wheel, focus motor rod mount, and a focus motor for $540. Both versions are available starting today. Today DJI introduced a new $440 gimbal that allows mirrorless camera users to take command of stabilization in videos of all sorts. This machine is simple-to-use, relatively small, and right on the high end of all the pro points. DJI suggests on their site that “due to limited new product availability,” they’ll only sell two units to each prospective customer.center_img This machine is able to work with a wide variety of cameras and accessories – pretty much anything that’ll fit with its holes and/or ports. Accessory connections include a 1/4” Mounting Hole, 3/8” Mounting Hole, Camera Control Port, Accessory Port, USB-C Port, and an RSA Port. Users will be able to connect wirelessly with the machine using Bluetooth 5.0, with an app for iOS or Android. The iOS app requires iOS 9 or above, and Android requires Android version 5 or above. Tested payload for this gimbal is under 2kg – that’s under 4.4 pounds. So don’t go attaching a big sack full of mercury or anything strange – that won’t work. Angular vibration range is ±0.02°, and maximum controlled rotation speed is 180°/s for pan, tilt, and roll axis control.last_img read more

first_imgConnected home appliances and smart devices are getting more and more common these days but not everyone may be confident in setting those up. Their added complexity means that you can no longer just plug an appliance or screw a bulb and just expect it to work. Sometimes, on-site, or in-home rather, installation and training are even needed to take full advantage of these new technologies and DISH’s new OnTech Smart Services is more than ready to provide exactly that. Connected appliances are pretty smart but not smart enough to set themselves up. At the very least, users have to connect them to the home network using the app designed for that product or brand. The number of competing brands means there’s quite a confusing mix of apps and platforms, some of which don’t even speak a single language.That’s where the OnTech Smart Services by DISH comes in. The new service’s technicians go to homes to do the installations for customers. That’s especially helpful for more complicated products like video doorbells and thermostats. They can even make finishing touches like TV mounting or power relocation.Going beyond the initial setup, OnTech personnel can also do one-on-one education to teach owners how to use the products. Many new smart home owners might not be aware of the full range of capabilities their new toys have and some don’t have the time to dig through all the menus and options available.OnTech Smart Services support products Google Nest, Ring, Linksys, Wemo, Roku®, Yale, Polk Audio, and Klipsch Audio. At the moment, it’s a limited rollout in a few markets in the US, including Atlanta, New York, Dallas/Ft. Worth, Sacramento, Denver, Salt Lake City, Houston, San Francisco, Kansas City, St. Louis, and Los Angeles.last_img read more

first_img More than 1,100 Georgia pediatricians have joined a new physician-led network that aims to improve quality of care and eventually contract for payments from insurers. The sign-ups represent roughly one-third of the pediatricians practicing in the state. Children’s Healthcare of Atlanta, the major pediatric hospital system in the metro area, helped create the nonprofit entity, called the Children’s Care Network. (MIller, 9/1) Health News Florida: State In Legal Battle Over Prescription Drug Benefits The San Jose Mercury News: Santa Clara County To Sever $300 Million Contract Over Valley Med Hospital Upgrade The governors of all six New England states have sent a letter urging the head of the U.S. Food and Drug Administration to tighten warnings on opioids.The governors said the FDA should require changes on labels for immediate release opioids to make sure patients and doctors understand the risk of addiction, overdose, neonatal abstinence syndrome and death associated with the drugs. (8/31) The Associated Press: New England Governors Urge FDA To Set Tougher Opioid Labels Pharmacy-benefit managers for the state-employee health insurance program are challenging an attempt to require them to repay $39.2 million to the Florida Department of Management Services. Medco Health Solutions, Inc. and Express Scripts, Inc., which are subsidiaries of the same holding company, have filed a series of legal petitions that were sent this month to the state Division of Administrative Hearings. (8/31) The service at issue, known as extended, or complex, nursing care, involves a nurse providing services in a person’s home for more than two hours at a time. Clients must have their services reauthorized periodically to continue receiving them. Data from the state Department of Social Services shows the denial rate for requests for extended nursing services has risen sharply since the beginning of the year. (Levin Becker, 9/1) This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.center_img Santa Clara County’s $300 million expansion and seismic upgrade at Valley Medical Center is already two years behind schedule — with no hope of opening next month in time for its latest deadline. Now, in an increasingly bitter dispute that played out Monday at the construction site, the county declared it intends to fire Turner Construction, the company overseeing the project and one of the country’s biggest builders, whom county officials blame for falling woefully behind on the job. (De Sa, 8/31) Kaiser Health News: A Third Of Ga. Pediatricians Join Together To Form Network To Improve Care Dr. David Burkons graduated from medical school and began practicing obstetrics and gynecology in 1973 – the same year of the Supreme Court’s landmark abortion decision in Roe v. Wade. Burkons liked delivering babies but he is also committed to serving his patients, including those who choose abortions. (Tribble, 8/31) State Highlights: Fla. Embroiled In Legal Fracas Over Prescription Drug Benefits; New England Governors Urge FDA To Toughen Opioid Warnings Health care stories are reported from Florida, Connecticut, California, Ohio and Georgia. Kaiser Health News: In Ohio, New Abortion Clinic Opens, Bucking National Trend The Connecticut Mirror: Uptick In Denials For Home Nursing Care Worries Families, Advocates last_img read more

first_img This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. The Associated Press: High Court Skeptical Of State Power To Gather Health Data The Wall Street Journal: Vermont’s Effort To Gather Data On Health-Care Costs Faces Supreme Court Test Vermont’s Green Mountain Care Board requires insurers to provide information on payments made to medical providers, hoping that by knowing what is paid for health care it can find ways to keep costs in check and improve efficiency and quality of care. At least 18 other states already have or are setting up similar databases, but Vermont has the boldest experiment in mind: eventually building a single-payer plan that would aim for universal coverage akin to programs in Canada and some European countries. … Vermont’s solicitor general, Bridget Asay, told the Supreme Court on Wednesday that Congress intended to encourage states to collect data that could provide insight into improving care or reducing expenses. She said the 2010 Affordable Care Act, which amended the 1974 law, “contemplated a robust federal-state partnership in health experimentation.” (Bravin and Radnofsky, 12/2) Some legislators and policymakers consider the databases important tools to improve care and reduce costs. (Gorn, 12/2) Reuters: U.S. Justices Cast Doubt On Scope Of Vermont Healthcare Data Law center_img California Healthline: Supreme Court To Hear Case Deciding Fate of All-Payers Claims Databases Members of the U.S. Supreme Court on Wednesday indicated that Vermont and 17 other states could be prevented from collecting healthcare information from certain employee health plan administrators. The nine justices heard a one-hour oral argument over whether a 2005 Vermont data collection law aimed at improving the quality of healthcare applies to self-funded insurance plans, which are most commonly used by large companies. (12/2) High Court Hears Oral Arguments On Vermont Health Care Data Law Some of the state insurers argued that federal law bars states from requiring insurers to supply data on the costs and outcomes of their services. But some policymakers counter that these databases are important in the effort to improve quality of care and control costs. The Supreme Court on Wednesday appeared skeptical that state officials have the power to require health insurers to turn over reams of data revealing how much they pay for medical claims. Most of the justices seemed to agree during a one-hour argument that efforts by Vermont and other states to collect and publicize the data conflict with federal law governing certain health plans. (Hananel, 12/2) last_img read more

first_img Stat: The Hospital Exec On New Generic Maker: Trying To Bring ‘Sanity’ Stat: Fact-Checking An Ad War Over Drug Prices, Celgene, And Bob Hugin Stat: SEC Charges Biotech Billionaire Philip Frost With Pump-And-Dump Fraud The Wall Street Journal: General Atlantic Takes Majority Stake In OneOncology, A Startup For Running Cancer-Doctor Practices Kaiser Health News: Unwitting Patients, Copycat Comments Play Hidden Role In Federal Rule-Making The rising cost of prescription drugs is an issue in midterm races across the country, but nowhere more so than in New Jersey, where one candidate is the recently retired CEO of an actual drug company. So we decided to take a look at the rhetoric in that race, pitting incumbent Sen. Bob Menendez against former Celgene boss Bob Hugin. In TV ads blanketing New Jersey (and Philadelphia and New York City), Menendez paints his opponent as a craven profiteer, raising prices on patients with no other options. But Hugin argues that Celgene has saved thousands of lives by giving away doses of its banner cancer drug for free to patients who can’t afford it. (Garde, 9/11) Stat: Pfizer Taps Two Neuroscience Startups For Incubator Prize Just months after Pfizer slashed hundreds of jobs in  its own neuroscience R&D program, the pharmaceutical giant is making notable investments in two Boston-based neuroscience startups. The company announced Wednesday that Tevard Biosciences and QurAlis will each receive one of Pfizer’s coveted “Golden Tickets”— a valuable voucher for the fees associated with renting a spot for one scientist for one year at LabCentral, a biotech incubator in Cambridge, Mass. For companies based elsewhere, the ticket also allows a start-up to set up shop at the noted space in Kendall Square. (Sheridan, 9/12) How PBMs Can End Up Pocketing Nearly $200 For A Bottle Of Pills Costing Less Than $6 News outlets report on stories related to pharmaceutical pricing. The New York Times: A Battle Plan For A War On Rare Diseases Boston Globe: In The Go-Go Biotech World, A Cautionary Tale Stat: Amid Anger Over Drug Prices, Former Pharma CEO Bob Hugin Runs For The Senate Bloomberg: The Secret Drug Pricing System Middlemen Use To Rake In Millions Private-equity firm General Atlantic has agreed to invest $200 million in a startup that aims to manage independent cancer-treatment clinics, the latest sign investors see opportunity in the health-services sector. The investment makes General Atlantic the majority owner of OneOncology, a startup that launched this month. Its founders, three cancer-treatment practices in Tennessee and New York, are the other owners and its first customers. (Evans, 9/12) File this under “If at first you don’t succeed, …” AmerisourceBergen (ABC), which is one of the nation’s largest pharmaceutical wholesalers, has conceded that its compounding business needs to be fixed, so the company has hired manufacturing experts to review procedures at a key facility in Memphis and postponed plans to resume shipments. (Silverman, 9/7) center_img Not everybody reads the legal notices inside the Ottumwa Courier. But in January, Iowa pharmacist Mark Frahm noticed something unusual in the paper. For years, Frahm’s South Side Drug bought pills from distributors, and dispensed prescriptions to the Wapello County jail. In turn, the pharmacy got reimbursed for the drugs by CVS Health Corp., which managed the county’s drug benefits plan. As he compared the newspaper notice with his own records, and then with the county’s, Frahm saw that for a bottle of generic antipsychotic pills, CVS had billed Wapello County $198.22. But South Side Drug was reimbursed just $5.73. So why was CVS charging almost $200 for a bottle of pills that it told the pharmacy was worth less than $6? And what was the company doing with the other $192.49? (Langreth, Ingold and Gu, 9/11) The Wall Street Journal: Big Pharma Catches Up With Biotech For the CEO of a biotech startup, there may be no bigger asset than a compelling sales pitch. Frank Reynolds had a great one. He hadn’t planned a career in biotechnology, the head of Cambridge-based InVivo Therapeutics would tell investors. His calling found him. (Saltzman, 9/8) The Wall Street Journal: Drug Distributor AmerisourceBergen Names New Finance Chief Angered by rising prices and persistent shortages of generic drugs, seven of the nation’s largest hospital systems have launched a new, not-for-profit manufacturer. The company, which was first discussed publicly earlier this year, starts with a $100 million in capital and loans, some of which will come from three philanthropic organizations, including the Laura and John Arnold Foundation. Civica Rx will contract with other companies to make more than a dozen generics and some sales will start in mid-2019. We spoke with Dan Liljenquist, a vice president at Intermountain Healthcare who initiated the project, about the possibilities and challenges. This is an edited version of our conversation. (Silverman, 9/6) Stat: AmerisourceBergen Scrambles Again To Fix A Troubled Compounding Facility Among the 30,000 attendees of the Rutherford Street Fair, sweating it out on the street between the zeppoles and deep-fried Oreos, was the pharmaceutical millionaire who wants to be their next senator. Bob Hugin, the former CEO of Celgene, spent Labor Day walking through the crowd with a phalanx of staff and volunteers, each with a sign and a T-shirt bearing his name. They chanted, cheered, and sloganeered as Hugin’s would-be constituents looked on, varyingly bemused or befuddled at the merry little militia demonstrating in their town. Hugin shook hands, posed for photos, and remembered to say “good to see you” but never “nice to meet you.” (Garde, 9/6) A proposal to sharply cut a drug discount program that many hospitals rely on drew some 1,400 comments when the Trump administration announced its plan last year. Hundreds appeared to come from patients across the country — pleas from average Americans whose treatments for diseases such as cancer depend on costly medicines. But a review of the responses found that some individuals were not aware they apparently had become part of an organized campaign to oppose what’s known as the “340B” program. (Tribble, 9/11) It was a great summer for big pharma stocks. Investors shouldn’t expect that trend to reverse this fall. As has become routine, biotechnology stocks had a strong summer. A broad index of those stocks is up about 15% this year and is near a record. This time, however, major pharmaceutical companies are joining in the rally. (Grant, 9/5) A decade ago, when their son Bertrand was still an infant, Matthew Might and his wife, Cristina, realized that there was something terribly wrong. When he cried, his eyes stayed dry; the lack of tears damaged his corneas and threatened blindness. Eventually, he suffered seizures, a movement disorder and a severe developmental delay. It took four years to discover the problem: Bertrand had inherited two mutations of the NGLY1 gene, which plays a key role in recycling cellular waste. That meant the child’s cells were choking on their own trash. (Weintraub, 9/10) This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. Philip Frost, a longtime biotech billionaire, was accused Friday of taking part in a pump-and-dump stock scheme that bilked investors out of $27 million. The Securities and Exchange Commission charged Frost and nine others in connection with what it described as a scheme to buy up shares in penny-stock biotechs, illegally promote the companies online, and then sell their shares before the bottom fell out. (Garde, 9/7) Drug distributor AmerisourceBergen Corp. ABC -0.35% said its finance chief Tim Guttman will retire in November and will be succeeded by Executive Vice President James Cleary. Mr. Guttman has served as the company’s chief financial officer since May 2012, and was previously vice president and corporate controller since joining the company in 2002. He will continue to serve as an adviser further into fiscal 2019 to ensure a smooth transition, the company said. (Shumsky, 9/10) last_img read more

first_img This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. We’d also like to send you special offers and news just by email from other carefully selected companies we think you might like. Your personal details will not be shared with those companies – we send the emails and you can unsubscribe at any time. Please tick here if you are happy to receive these messages.By submitting your information, you agree to the Terms & Conditions and Privacy & Cookies Policy. Sign up for the Mobile NewsletterSign Up Please keep me up to date with special offers and news from Goodtoknow and other brands operated by TI Media Limited via email. You can unsubscribe at any time. After being arrested over cocaine allegations, Japanese actor Pierre Taki was removed from SEGA’s Judgment, but now a replacement has been found. The actor himself has been completely scrubbed from the game as a response to his arrest, with SEGA seemingly cutting all ties with him. Kyohei Hamura, the intimidating captain of the Matsugane Family., will now be portrayed by a new face, although the lip-syncing and dialogue will remain the same. When Taki’s arrest emerged, there were fears amongst fans that the western release of Judgment might be delayed or cancelled entirely. Luckily, the planned June 25, 2019 release date remains untouched, meaning it’s only a couple of months until we get our hands on the crime caper. Known as Judge Eyes in Japan, physical and digital copies of the game were pulled following Taki’s arrest, and a patch will presumably be released with the new actor. We had a chance to play a few hours of Judgment (prior to its changes) a few months ago, and came away incredibly impressed by the evolution it makes to Yakuza: ‘Judgment doesn’t rewrite the rulebook Yakuza has strictly abided by for over a decade now, but it does tear out a few pages and make its own mark with some brave yet innovative changes to the formula.’Are you happy with the changes SEGA has made to Judgment? Let us know on Facebook and Twitter @trustedreviews. Show More Unlike other sites, we thoroughly review everything we recommend, using industry standard tests to evaluate products. We’ll always tell you what we find. We may get a commission if you buy via our price links.Tell us what you think – email the Editorlast_img read more

first_imgApple has announced a voluntary recall for AC wall plug adapters designed for use in the United Kingdom, following limited reports of broken three-pronged plugs causing electric shocks.The company says it is aware of six incidences worldwide where the charging accessories caused an electric shock when touched, and has issued the voluntary recall as a precautionary measure.These specific adapters were designed for the UK, Hong Kong and Singapore markets and were shipped with iOS and Mac devices between 2003 and 2010. They were also part of the World Travel Adapter Kit sold by the company.Related: Best iPhone 2019The standard USB power adapters are not affected by the limited issues, but if you’re using one of the specific adapters you can seek an exchange via Apple’s support website.In the Newsroom post, Apple wrote: “Because customer safety is a top priority, Apple is asking customers to stop using affected plug adapters. Customers should visit apple.com/support/three-prong-ac-wall-plug-adapter for details about how to exchange them for new adapters.“An affected three-prong plug adapter is white, with no letters on the inside slot where it attaches to the main Apple power adapter. See website for more details and images to identify an affected adapter.”Previously, in 2016, Apple had issued a recall for adapters designed for use in continental Europe, Australia, New Zealand, South Korea, Argentina, and Brazil. That too came after reports of electric shock risks.Do you have one of the plugs in question? Let us know @TrustedReviews on Twitter.  This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. We’d also like to send you special offers and news just by email from other carefully selected companies we think you might like. Your personal details will not be shared with those companies – we send the emails and you can unsubscribe at any time. Please tick here if you are happy to receive these messages.By submitting your information, you agree to the Terms & Conditions and Privacy & Cookies Policy. Sign up for the Mobile NewsletterSign Up Please keep me up to date with special offers and news from Goodtoknow and other brands operated by TI Media Limited via email. You can unsubscribe at any time. Show More Unlike other sites, we thoroughly review everything we recommend, using industry standard tests to evaluate products. We’ll always tell you what we find. We may get a commission if you buy via our price links.Tell us what you think – email the Editorlast_img read more

first_imgAmazon Prime Day Deals This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Sign up for the Mobile NewsletterSign Up Please keep me up to date with special offers and news from Goodtoknow and other brands operated by TI Media Limited via email. You can unsubscribe at any time. ——————————————————————————————————–Grab these great Prime Day savingsSave £40 on the Kindle Paperwhite£160 off the Dell Inspiron 14 Chromebook We’d also like to send you special offers and news just by email from other carefully selected companies we think you might like. Your personal details will not be shared with those companies – we send the emails and you can unsubscribe at any time. Please tick here if you are happy to receive these messages.By submitting your information, you agree to the Terms & Conditions and Privacy & Cookies Policy. Want to stay up to date with Amazon Prime Day 2019? We’ve got you covered. For more amazing offers, follow us @TrustedDealsUK.We may earn a commission if you click a deal and buy an item. That’s why we want to make sure you’re well-informed and happy with your purchase, so that you’ll continue to rely on us for your buying advice needs. Update: We hate to say it, but Amazon’s Huawei MateBook Prime Day deal is long gone. If you don’t want to miss out on great offers like this in the future then give us a follow @TrustedDeals.Still rooting around for a reet good laptop bargain on Prime Day? Then this Huawei MateBook 13 deal from Amazon is for you.Buy now: Huawei MateBook 13 for just £679.99.Boasting a 13-inch 2K (2160×1440) display with skinny 4.4mm bezels, maximum brightness of 300 nits and full coverage of the sRGB colour gamut, and measuring just 286 x 211 x 14.9mm the Huawei MateBook 13 is a slender Windows 10 laptop that’s ideally suited for work on the go indoors or in direct sunlight. Huawei MateBook 13 Amazon Prime Day DealHuawei MateBook 13 – Intel Core i5, 256GB SSDPick up this 13-inch Huawei laptop with a 13-inch 2K display, Intel Core i5 CPU, 8GB RAM, and a 256GB SSD for less this Prime Day.Amazon|Save £69.01|Now £679.99View DealNow £679.99|Save £69.01|AmazonHuawei MateBook 13 – Intel Core i7, 512GB SSDGet the Core i7 version of the Huawei MateBook 13 with 512GB of storage for less than the standard RRP from Amazon.Amazon|RRP £1099.99|New price £899.00View DealNew price £899.00|RRP £1099.99|Amazon Show More Unlike other sites, we thoroughly review everything we recommend. We use industry standard tests to evaluate products in order to assess them properly. We’ll always tell you what we find. Trusted Reviews may get a commission if you buy through our links. Tell us what you think. Under the hood you get an Intel Core i5-8265U processor from the Whiskey Lake range, promising excellent performance per Watt, meaning that you’ll be free to work off of the mains, should you need to, and not have to worry about the battery levels dropping through the floor. The particular model on offer comes with 8GB of RAM and 256GB of SSD storage. However, you can also pick up a Huawei MateBook 13 from Amazon now with a faster Intel Core i7-8565U processor, 8GB of RAM and a larger 512GB SSD for £899 – which is less than the usual price of £1099.99. Note that this isn’t a Prime Day deal per se, Amazon just says that £899 is its standard price for this laptop, which is a saving of £200.99. Stock is limited though, so if your on the fence, cash in now. You should also note that Huawei has been in the headlines for not the best reasons recently – it’s one of the more prominent victims of the ongoing U.S. vs China trade dispute. However, both Microsoft and Intel have both recently confirmed that they will continue to support Huawei devices. After a brief spell, Microsoft pulled Huawei laptops from its official store – now they’re back again. While the future of its phones is looking a lot less sure at the time of writing, picking up a Huawei laptop now seems like a much safer bet.  Huawei MateBook 13 Amazon Prime Day DealHuawei MateBook 13 – Intel Core i5, 256GB SSDPick up this 13-inch Huawei laptop with a 13-inch 2K display, Intel Core i5 CPU, 8GB RAM, and a 256GB SSD for less this Prime Day.Amazon|Save £69.01|Now £679.99View DealNow £679.99|Save £69.01|AmazonHuawei MateBook 13 – Intel Core i7, 512GB SSDGet the Core i7 version of the Huawei MateBook 13 with 512GB of storage for less than the standard RRP from Amazon.Amazon|RRP £1099.99|New price £899.00View DealNew price £899.00|RRP £1099.99|Amazonlast_img read more

first_img Recommended For YouOman urges Iran to release seized tankerDavid Rosenberg: Deflation is still the No. 1 threat to global economic stability — and central banks know itTrans Mountain construction work can go ahead as National Energy Board re-validates permitsBank of Canada drops mortgage stress test rate for first time since 2016The storm is coming and investors need a financial ark to see them through The Canadian Press Metro hikes dividend, reports sales up from year ago Adjusted profit up More Join the conversation → Featured Stories Sponsored By: Reddit Email MONTREAL — Metro Inc. raised its dividend as it reported a first-quarter profit of $203.1 million.The grocery and drug store company says it will pay a quarterly dividend of 20 cents per share, up from 18 cents per share.Metro reported its profit amounted to 79 cents per diluted share for the 12 weeks ended Dec. 22, compared with a profit of nearly $1.3 billion or $5.67 per diluted share for the same period a year earlier.At that time, it benefited from the sale of its stake in Alimentation Couche-Tard Inc. to help fund its deal to buy the Jean Coutu Group Inc.On an adjusted basis, Metro says it earned $172.2 million or 67 cents per diluted share for its latest quarter, up from an adjusted profit of $126.7 million or 55 cents per diluted share a year earlier.Analysts on average had expected a profit of 68 cents per share for the quarter, according to Thomson Reuters Eikon.Sales for what was the company’s first quarter totalled $3.98 billion, up from $3.11 billion a year earlier.  What you need to know about passing the family cottage to the next generationcenter_img ← Previous Next → Metro Inc. raised its dividend as it reported a first-quarter profit of $203.1 million.Canadian Press/Paul Chiasson / THE CANADIAN PRESS 0 Comments advertisement Facebook Twitter Share this storyMetro hikes dividend, reports sales up from year ago Tumblr Pinterest Google+ LinkedIn January 29, 20199:32 AM EST Filed under News Retail & Marketing Commentlast_img read more

Chevy Bolt, Baojun E100 Push GM Global Plug-In Sales Ahead Of U.S. Author Liberty Access TechnologiesPosted on September 12, 2018Categories Electric Vehicle News Electrified transmissions? Let’s have a look at what this General Motors executive is talking about.So much uncertainty in the future of OEMs’ electrification plans is forever present. Thus, Autoline’s John McElroy interviews General Motors’ top dog for global transmission electrification, to get a better idea of what’s in store.Check Out These Stories: Executive Director of Global Transmission Electrification at GM, Mike Anderson titled his recent share “Navigating the Uncertainty.” While this may come across as pro- or anti-electric vehicles, one can certainly understand the dilemma. As electrification slowly unfolds and eventually becomes the norm, how can OEMs bank on the tried-and-true practices, all while preparing for the imminent future? From an EV aficionado perspective, legacy automakers aren’t doing enough. But in reality, people like Anderson seem to be aware of and on top of it.Anderson realizes that flexibility is paramount and having the team ready is key. Now, it’s all a matter of the “if” and “when.” While we’d love to say that legacy automakers aren’t planning or doing enough, it all comes with the territory.He reveals that even with an ICE or hybrid car today, electrified transmissions are already key. When it comes to transmissions for electric cars, next-gen transmission development is already on par and ready to go. Anderson admits that GM is already in “Lane 2” in terms of the development of this tech. He assures that for some EVs that are performance capable, a two-speed transmission makes sense.GM is taking notes and has been for years in regards to its Chevrolet Volt and Bolt EV. Anderson admits that while some of the data was expected, the automaker has learned quite a bit along the way. Check out the video above for more information.Video Description via Autoline Network on YouTube:GM: Navigating the Uncertainty – CAR MBS 2018Automakers have been adding more and more gears to transmissions over the years. But that trend won’t last, according to Mike Anderson, the Executive Director of Global Transmission Electrification at GM. With the move to EVs, he says were about to see more electrified transmissions in our vehicles. GM: “At least” 20 New EVs To Debut In Next 5 Years, Two in Next 18 Months GM CEO Barra Acknowledges Tesla’s “Very Capable” Cars Source: Electric Vehicle News read more

first_imgSource: Amada Miyachi Europe Manufacturing batteries for EVs requires specialized equipment, and battery makers require different systems depending on battery type, tab material and thickness, and production volume. Amada Miyachi Europe is a company that provides a range of resistance and laser welding equipment for just this purpose.Most recently, the company provided resistance welding equipment to German battery system manufacturer LION Smart for the development of a proprietary new battery. LION Smart’s LIGHT Battery provides 100 kWh of energy, and keeps the cells cool by immersing them in 3M Novec cooling fluid.The LIGHT Battery was designed for fully automated production. It uses infrared communication instead of wires, which frees up the cylindrical cells for a high packing density.Amada Miyachi Europe provides six laser welding technologies and four resistance welding technologies, as well as micro-arc (or pulse-arc) welding. Source: Electric Vehicles Magazinelast_img read more

first_imgShare on Twitter Share on Messenger Share on Facebook Topics Shares00 Horse racing Share on Twitter Share via Email First published on Tue 19 Aug 2008 19.01 EDT Following a series of near-misses at the highest level, Raven’s Pass is 5-4 favourite with bookmakers Blue Square to gain a deserved victory in the Group Two Celebration Mile at Goodwood on Saturday. John Gosden’s colt, beaten just a head by Henrythenavigator in the Sussex Stakes last month, could be opposed by last weekend’s impressive Hungerford Stakes winner, Paco Boy. Richard Hannon’s three-year-old is 3-1, with Bankable on offer at 9-2.The Prix Morny is the next feature race in Deauville’s run of Group One events on Sunday and the prestigious two-year-old prize will again be a target for British and Irish trainers, who between them have won the last three renewals. Since you’re here… Raven’s gets another chance at Goodwood Peter Chapple-Hyam, successful with Dutch Art two years ago, plans to run Sayif, who is reported in “good order”. Sayif has yet to win a race but has twice been placed in Group Two company. Prolific, winner of the Richmond Stakes last time, holds an entry in the Morny but is unlikely to figure after today’s first forfeit stage. “It will almost certainly be too soft for him in France,” said Harry Herbert, who manages the Highclere Thoroughbred syndicate, owners of Prolific. Prolific had already been scratched from York’s Gimcrack Stakes before the weather intervened. “He is a top-of-the-ground horse and we will wait for the Mill Reef Stakes at Newbury with him,” said Herbert. “His principal target is the Middle Park. He’s progressing physically and is a gutsy trier.” Irish trainer David Wachman is also considering the Morny for his Bushranger following the colt’s fine effort in defeat at The Curragh last month. York is not the only racetrack to be hit by the recent wet weather. Today’s meeting at Carlisle has also been lost, while there is a 7am inspection to determine if racing can go ahead at Hamilton. Share on Facebookcenter_img Read more Ron Cox Support The Guardian Share via Email Tue 19 Aug 2008 19.01 EDT Share on Pinterest … we have a small favour to ask. The Guardian will engage with the most critical issues of our time – from the escalating climate catastrophe to widespread inequality to the influence of big tech on our lives. At a time when factual information is a necessity, we believe that each of us, around the world, deserves access to accurate reporting with integrity at its heart.More people are reading and supporting The Guardian’s independent, investigative journalism than ever before. And unlike many news organisations, we have chosen an approach that allows us to keep our journalism accessible to all, regardless of where they live or what they can afford. But we need your ongoing support to keep working as we do.Our editorial independence means we set our own agenda and voice our own opinions. Guardian journalism is free from commercial and political bias and not influenced by billionaire owners or shareholders. This means we can give a voice to those less heard, explore where others turn away, and rigorously challenge those in power.We need your support to keep delivering quality journalism, to maintain our openness and to protect our precious independence. Every reader contribution, big or small, is so valuable. Support The Guardian from as little as $1 – and it only takes a minute. Thank you. Share on LinkedIn The Recap: sign up for the best of the Guardian’s sport coverage Horse racing Share on WhatsApp Reuse this contentlast_img read more

first_imgThis previous post highlighted facts and figures from SEC enforcement of the FCPA in 2015.This post highlights facts and figures from corporate DOJ FCPA enforcement in 2015. (See here for a similar post from 2014, here for a similar post from 2013, here for a similar post from 2012, here for a similar post from 2011, and here from 2010).When reviewing the statistics below, keep in mind that there were only 2 corporate FCPA enforcement actions in 2015. Thus, certain of the below statistics are largely meaningless, yet nevertheless highlighted for comparative purposes.Settlement Amounts and SpecificsIn 2015, the DOJ brought 2 corporate FCPA enforcement actions (the lowest number of corporate DOJ FCPA enforcement actions since 2006).By comparison, in 2014, the DOJ brought 7 corporate FCPA enforcement actions; in 2013 the DOJ brought 7 corporate enforcement action; in 2012 the DOJ brought 9 corporate FCPA enforcement actions; in 2011 the DOJ brought 11 corporate enforcement actions; and in 2010 the DOJ brought 17 corporate enforcement actions.  (Note:  these figures  use the “core” approach to FCPA statistics – see here for the prior post – an approach also endorsed by the DOJ – see here).In the 2 corporate FCPA enforcement actions from 2014, the DOJ collected approximately $24.2 million in criminal fines.By comparison, in the 7 corporate FCPA enforcement actions from 2014, the DOJ collected approximately $1.25 billion in criminal fines (an all-time record in terms of yearly FCPA settlement amounts);  in the 7 corporate FCPA enforcement actions from 2013, the DOJ collected approximately $420 million in criminal fines; in 2012, the DOJ collected approximately $142 million in criminal fines; in 2011, the DOJ collected approximately $355 million in criminal fines ($504 million including the $149 million forfeiture in the Jeffrey Tesler individual enforcement action); and in 2010, the DOJ collected approximately $870 million in criminal fines.Corporate DOJ FCPA enforcement in 2015 ranged from $17.1 million (Louis Berger) to $7.1 million (IAP Worldwide). Both enforcement actions were DOJ only and involved privately-held companies.In the 1 corporate FCPA enforcement actions where an analysis was possible, the DOJ agreed to a criminal fine at the minimum range suggested by the sentencing guidelines.[Note – the IAP Worldwide enforcement action was resolved via an NPA and the DOJ does not set forth a guidelines range in NPAs]Corporate vs. Individual ProsecutionsOf the 2 corporate DOJ enforcement actions in 2015, 2 (100%) resulted in related DOJ prosecutions of company employees. Notwithstanding this 2015 statistic, as highlighted in this prior post, approximately 75% of DOJ corporate enforcement actions since 2008 have not (at least yet) resulted in any DOJ charges against company employees.The DOJ announced 8 individual FCPA enforcement actions in 2015 (Harder, Rama, Hirsch/McClung, Garcia, Condrey and Rincon / Shiera) in 6 core actions.Stay tuned for future posts specifically about DOJ and SEC individual FCPA enforcement actions in 2015.NPAs / DPAsIn 2015, 2 of the 2 (100%) DOJ corporate enforcement actions were resolved via an NPA (IAP Worldwide) or a DPA (Louis Berger).By way of comparison, in 2014, 5 of the 7 (71%) DOJ corporate enforcement actions included an NPA or DPA; in 2013, 100% of corporate DOJ enforcement actions involved either an NPA or DPA; in 2012 100% of corporate DOJ enforcement actions involved either an NPA or a DPA;  in 2011 82% of corporate DOJ enforcement actions involved either an NPA or DPA; and in 2010 94% of corporate DOJ enforcement actions involved either an NPA or DPA.Since 2010, approximately 85% of corporate DOJ enforcement actions have involved either an NPA or DPA.Voluntary DisclosuresOf the 2 DOJ corporate enforcement actions in 2015, 1 enforcement action (50%) was the result of a corporate voluntary disclosure.[Note – the Louis Berger DPA states as follows:  “after the government had made [the company] … aware of a False Claim Act investigation, [the company] conducted an internal investigation, discovered potential FCPA violations, and voluntarily self-reported to the [DOJ] the misconduct.” The origin of the IAP Worldwide action is unclear as the NPA makes no mention of voluntary disclosure or other potential origins of the action.]By way of comparison, of the 7 corporate DOJ FCPA enforcement actions in 2014, 2 enforcement actions (29%) were the result of corporate voluntary disclosures; in 2013 57% of corporate FCPA enforcement actions were the result of corporate voluntary disclosures or the direct result of a related voluntary disclosure; in 2012, 78% of corporate FCPA enforcement actions were the result of corporate voluntary disclosures or casually related to previous corporate voluntary disclosures; in 2011, 73% of corporate FCPA enforcement actions were the result of corporate voluntary disclosures.MonitorsOf the 2 corporate DOJ FCPA enforcement actions in 2015, 1 (50%) enforcement action (Louis Berger) resulted in a corporate monitor.By way of comparison, of the 7 corporate DOJ FCPA enforcement actions in 2014, 1 (14%) resulted in a corporate monitor; of the 7 corporate DOJ FCPA enforcement actions in 2013, 4 enforcement actions (57%) involved a monitor; of the 9 corporate DOJ FCPA enforcement actions in 2012, 3 enforcement actions (33%) involved a monitor; of the 11 corporate DOJ FCPA enforcement actions in 2011, 1 enforcement action (9%) involved a corporate monitor; of the 17 corporate DOJ enforcement actions in 2010, 7 enforcement actions (41%) involved a corporate monitor.This remainder of this post provides an overview of corporate DOJ FCPA enforcement in 2015.*****Louis Berger Int’l.  (July 17th)See here for the prior postCharges:  Conspiracy to violate the FCPA’s anti-bribery provisionsResolution Vehicle:  DPAGuidelines Range:  $17.1 million – $34.2 millionPenalty:  $17.1 million.Disclosure:  The DPA states: “after the government had made [the company] … aware of a False Claim Act investigation, [the company] conducted an internal investigation, discovered potential FCPA violations, and voluntarily self-reported to the [DOJ] the misconduct”Monitor:  YesIndividuals Charged:  YesIAP Worldwide Services Inc.  (June 16th)See here for the prior postCharges:  Not applicable.Resolution Vehicle:  NPAGuidelines Range:  None set forth in the NPA.Penalty:  $7.1 million.Disclosure:  Unclear, the NPA makes no mention of voluntary disclosure or other potential origins of the action.Monitor:  NoIndividuals Charged:  Yeslast_img read more

first_img Source:http://americanpainsociety.org/220-pain-rehab-programs-without-opioids-proving-effective Jun 27 2018American Pain Society Study Reports Significant Quality of Life Improvements New research, published this month by the American Pain Society (APS), adds to burgeoning scientific evidence showing that interdisciplinary pain rehabilitation programs are an effective alternative to opioids for chronic pain management. Despite several studies documenting favorable outcomes, access to multi-modal pain management programs remains out of reach for most patients due to inadequate insurance coverage. This discourages providers from opening new interdisciplinary pain clinics.”Doctors refer patients to specialty pain clinics, usually filled to capacity, so desperation sets in and the next stop could be a dealer on the street,” said William Maixner, DDS, PhD, president of the American Pain Society. “We need more specialty pain clinics, but paltry reimbursements offer no incentives for opening more programs.”Related StoriesAre Chronic Pain Relief Drugs for Children Effective?Family members’ drugs may be risk factor for overdose in individuals without prescriptionsBirth, child outcomes linked with maternal opioid use during pregnancyThe new study appears in the June issue of The Journal of Pain, the APS peer-review publication. Researchers from Mayo Clinic hypothesized that patients with chronic pain not using opioids and those tapered off opioids during treatment would experience significant improvements in self-report and performance-based functional outcomes from treatments in interdisciplinary pain rehabilitation programs (IPRPs).Results showed that patients who were tapered off opioids showed improvement comparable to patients not taking opioids and experienced sustained improvements in functioning six months after treatment. The authors concluded their findings suggest that regardless of previous opioid use status, IPRP treatment leads to sustained functional restoration for chronic pain for an enhanced degree of daily functioning.”The ultimate aim of IPRP is not to alleviate pain or produce short-term functional gains, but rather to foster sustained benefits that patients can continue for the remainder of their lives,” the authors wrote.”Biopsychosocial approaches to pain assessment can enhance treatment outcomes by better matching patients to appropriate therapies. More and more studies are showing that psychosocial pain treatments work and are making a difference,” Maixner said. “Medicare, Medicaid and private insurers, therefore, must offer better coverage for biopsychosocial pain management as part of a comprehensive national effort to bring relief to people with chronic pain without resorting to opioids.”​​​​last_img read more

first_img Source:https://www.iospress.nl/ios_news/early-treatment-with-nusinersen-can-mean-better-outcomes-for-babies-with-spinal-muscular-atrophy/ Jul 17 2018Spinal muscular atrophy (SMA) is a genetic disease that affects motor neurons in the spinal cord, resulting in muscle atrophy and widespread weakness that eventually impair swallowing and breathing. A new study in the Journal of Neuromuscular Diseases finds that children with SMA type 1 can achieve improvements in motor function after six months of treatment with the drug nusinersen, particularly when treatment began before seven months of age. These findings highlight the importance of early detection of SMA through newborn screening.”Our findings add to the increasing body of evidence that early diagnosis and initiation of treatment is fundamental for patients with infantile-onset spinal muscular atropy,” explained lead investigator Janbernd Kirschner, MD, of the Department of Neuropediatrics and Muscle Disorders, Medical Center, Faculty of Medicine, University of Freiburg, and Coordinator of the TREAT-NMD Clinical Trial Coordination Centre (CTCC), Freiburg (Germany).SMA type 1 is the most common and also most severe subtype of SMA. After diagnosis infants with SMA type 1 rarely achieve improvements of motor function or attain motor developmental milestones. Within the last few years, there has been a promising approach for the development of novel drugs intervening the pathophysiology of SMA. Among these, nusinersen is the first drug specifically approved to treat SMA. Prior to approval in Europe, nusinersen was provided to patients with SMA type 1 within an Expanded Access Program (EAP). In contrast to the previous clinical trials, children of different age groups and different stages of the disease were treated with nusinersen within the EAP.The current prospective, open-label study conducted in Germany reports outcomes from 61 children with SMA type 1 treated with nusinersen between November 2016 and June 2017 who met EAP guidelines. Patients ranged in age from a few months to almost 8 years. Symptoms generally appeared within the first three months of life and most babies were diagnosed before six months of age. Prior to treatment, more than jhalf of the children required ventilation support, 20% had already undergone a tracheostomy, and more than half required a feeding tube.Related StoriesChaos in the house and asthma in children – the connectionGenetic contribution to distractibility helps explain procrastinationWhy Mattresses Could be a Health Threat to Sleeping ChildrenAlthough improvements in motor function are not expected within the natural course of the disease, the researchers observed improvements in motor function after six months of nusineresen therapy in many patients, and 34% of the patients achieved new motor developmental milestones. The response to treatment strongly correlated with age at onset of treatment. Overall, greater improvements were seen in children who began treatment at seven months or younger compared to those who started treatment after seven months. Improvements could still be seen in patients who started therapy between two and four years of age, although the magnitude of the changes was less than those for infants. Despite six months of treatment, none of the children were able to stand or walk independently, and many still required ventilator support and tube feeding.The findings of this study add to the increasing body of evidence that early diagnosis and initiation of treatment are fundamental for patients with infantile onset spinal muscular atrophy highlighting the importance of the implementation of a newborn screening. “We have evidence that there is a critical therapeutic time window for delivery of SMN-targeted therapies,” noted Dr. Kirschner. “The implementation of newborn screening for SMA is crucial to allow pre-symptomatic diagnosis.Based on the results of this study, the SMArtCARE project aims to collect further data of all SMA patients to evaluate outcomes in a broader spectrum of SMA, the effect of treatment after prolonged treatment periods, and also to what extent changes in motor function affect patients’ and caregivers’ quality of life.SMA is caused by mutations in the survival motor neuron (SMN) 1 gene, which codes for survival motor neuron protein. This leads to loss of function. The SMN 1 gene is located on chromosome 5q13. Nusinersen, the first drug to be approved for SMA, is an antisense oligonucloetide which leads to increased expression of more full-length and functional SMN protein by functionally converting the SMN2 gene into the SMN1 gene. Nusinersen is injected into the spinal canal to allow it to distribute to the central nervous system.last_img read more

first_imgJul 18 2018Settling youngsters down to sleep at night isn’t always easy. Recent research suggests that the amount of exposure children have to bright light in the hour leading up to bedtime -; whether emanating from light bulbs or electronic devices -; can have a big impact on sleep-related behavior.There’s chemistry behind it. Our circadian rhythm -; a kind of 24-hour internal brain clock that cycles regularly between sleepiness and alertness -; employs melatonin, the body’s natural sleep-inducing hormone. Melatonin is highly sensitive to light. As daylight dims toward the end of the day, our bodies are programmed to react to the reduction of light by increasing the production of melatonin. It’s nature’s way of ushering us toward sleep. Artificial light, however, can disrupt the circadian cycle by inhibiting the production of melatonin.Related StoriesDynamic Light Scattering measurements in concentrated solutionsMore than 936 million people have sleep apnea, ResMed-led analysis revealsSleep makes synapses ready for new learningResearch into the effects of light on preschool-age children found that youngsters are particularly sensitive to light exposure in the hour prior to bedtime. (Children’s clear crystalline eye lens and large pupil size render them generally more sensitive to light than adults.) According to some researchers, evening light exposure, with its melatonin-suppressing effect, may increase the likelihood of sleep disturbances in preschool-age children. When little ones shuffle out of a dark or dimly lit bedroom to tell parents “I’m thirsty” or “I heard a strange noise,” the bright light they encounter has been found to reduce their melatonin production, making it all that much harder for them to fall asleep when back in bed. Even reading bedtime stories in a brightly lit room can make it harder to fall asleep at story’s end. Dimming the ambient light, in both the child’s room and whatever spaces they might walk into, maybe a wise approach whenever possible.Mobile electronic devices, with their bright white screens, pose a similar risk. As many as 90% of preschool-age youngsters use devices, often during the hour before bedtime. But it’s not only preschoolers; youngsters of all ages find themselves glued to screens as the very last activity of their day. Studies found that following light exposure, melatonin remains suppressed for nearly an hour after the lights go off -; time for tossing and turning and missing out on essential shut-eye. Parents might declare the last hour prior to bedtime a device-free period, or insist that youngsters slide the brightness setting way down on their handheld electronics.Source: https://www.family-institute.org/last_img read more

first_imgAug 13 2018The use of benzodiazepines and related drugs (Z drugs) is associated with a modestly increased risk of Alzheimer’s disease, according to a recent study from the University of Eastern Finland. The risk increase was similar with both benzodiazepines and Z drugs regardless of their half-life. The results were published in Acta Psychiatrica Scandinavica.Related StoriesResearchers identify brain somatic mutations linked to Alzheimer’s diseaseArtificial DNA can help release active ingredients from drugs in sequence$4.23 million NIH grant to support development of Cleveland Alzheimer’s Disease Research CenterEven though the increased risk for Alzheimer’s disease was small in this study, the threshold for prescribing benzodiazepines and related drugs should be high enough due to their several adverse effects and events, such as falls. These medications are commonly used for sleep problems, but their effectiveness for this indication diminishes over weeks or months. However, the risk of adverse events remains in longer-term use.The study was conducted in the nationwide MEDALZ cohort which included all Finnish community dwellers with newly diagnosed Alzheimer’s disease in 2005-2011 (70,719 persons), and their age, sex and region of residence matched controls (282,862 persons). Medicine use since 1995 was extracted from the Finnish Prescription Register. Many chronic disorders, substance abuse, socioeconomical position and use of antidepressants and antipsychotics were taken into account. To account for reverse causality, drug use within 5 years before Alzheimer’s disease diagnosis was not taken into account. Source:http://www.uef.fi/-/bentsodiatsepiinien-kaytto-on-yhteydessa-kohonneeseen-alzheimerin-taudin-riskiinlast_img read more

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Required fields are indicated by an asterisk (*) A Longer Lifespan—No Dieting RequiredWe’ve known for decades that when animals eat dramatically less, they live longer and stay healthier. But surviving on far fewer calories is no picnic. Now, using a specific molecule produced every day by our own cells, researchers might have found another way to prolong our lifespan—no extreme dieting required.Lectures Aren’t Just Boring, They’re Ineffective, Too Are your lectures droning on? Change it up every 10 minutes with more active teaching techniques and more students will succeed, researchers say. A new study finds that undergraduate students in classes with traditional stand-and-deliver lectures are 1.5 times more likely to fail than students in classes that use more stimulating, so-called active learning methods.Blockbuster Big Bang Result May Fizzle  The biggest discovery in cosmology in a decade could end up fizzling out. Eight weeks ago, researchers reported finding evidence of the massive inflation of our universe immediately following the big bang. Many scientists hailed the result as the big bang’s “smoking gun.” But now, some scientists are saying that there’s a problem with the results.West Antarctic Ice Sheet Is CollapsingA disaster may be unfolding—in slow motion. Scientists have reported that a key glacier holding the massive West Antarctic Ice Sheet together is starting to collapse. In the long run, they say, the entire ice sheet is doomed, which would release enough meltwater to raise sea levels by more than 3 meters.Drug Could Protect Against Radiation ExposureIt may not work against Godzilla, but a new drug could protect people from deadly doses of radiation. The compound, already in clinical trials to treat a blood disorder, may also make radiation therapy for cancer safer.MERS Situation Not an Emergency Yet, WHO Panel SaysDespite a recent dramatic rise in cases, a World Health Organization panel stopped short of declaring the deadly new virus Middle East respiratory syndrome (MERS) a public health emergency of international concern. However, it did call on countries on the Arabian Peninsula to improve their hospital hygiene and help in carrying out much-needed studies on how MERS spreads. read more

first_img Click to view the privacy policy. Required fields are indicated by an asterisk (*) Remember Yucca Mountain? In another turn in the 27-year odyssey of the proposed nuclear waste repository in Nevada, a key safety evaluation published yesterday by the Nuclear Regulatory Commission (NRC) gives it a thumbs up. The 781-page report concludes that the proposed site, as described in a 2008 application by the U.S. Department of Energy (DOE), includes “multiple barriers to isolate radioactivity from the environment” for hundreds of thousands of years, commission staff said in a statement. That should allow it to comply with standards to protect ground water and people in the distant future.The lengthy document is the second of five assessment volumes to be published on Yucca, which would theoretically hold up to 77,000 tons of highly radioactive waste for up to 1 million years after it would be sealed. Chapters systematically assess the geology of the site and nearby aquifer, how waste will be packaged and stored, and the fate of the “drip shield” that is intended to protect the packaged waste from ground water. “DOE has demonstrated compliance with the NRC regulatory requirements for postclosure safety,” the document states.The Yucca site was designated in 1987 legislation as a repository and has faced political opposition in Nevada ever since. In 2008, DOE submitted a license application to open the repository, but withdrew it 2 years later. In response, the states of Washington and South Carolina—both large producers of nuclear waste—and others filed suit. Last year, a court ordered NRC to move forward with its review and licensing process. The Nuclear Energy Institute in Washington, D.C., an industry group, hailed the new report. “This technical evaluation provides strong support for our belief that the Yucca Mountain site is appropriate for an underground repository for used nuclear fuel,” the group said. The Republican-led House of Representatives Energy and Commerce Committee called the report “game-changing.”“[T]his is a major triumph of the [scientific] community of repository design and performance assessment,” said nuclear engineering professor Joonhong Ahn of the University of California, Berkeley, in an e-mail to ScienceInsider. “Having said this, there are still numerous hurdles ahead” before Yucca can open, he wrote. In addition to the other three required assessment volumes, he noted, the NRC commissioners themselves must rule on the application. Even if DOE receives the license, he adds, it may decide not to proceed.For its part, the state of Nevada vowed to continue its long-standing fight against the Yucca plan. “The NRC licensing board has admitted more than 200 Nevada contentions challenging the safety and environmental impacts of the proposed repository, and Nevada is prepared to aggressively prosecute these challenges. It is not apparent that the [NRC report] specifically addressed these and other safety contentions,” the state said in a statement. Emailcenter_img Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe Sign up for our daily newsletter Get more great content like this delivered right to you! 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first_imgSTEPHAN SCHMITZ Hidden conflicts? Pharma payments to FDA advisers after drug approvals spark ethical concerns Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe FDA’s revolving door: Companies often hire agency staffers who managed their successful drug reviews Related story Email Through web searches and online services such as LinkedIn, however, Science has discovered that 11 of 16 FDA medical examiners who worked on 28 drug approvals and then left the agency for new jobs are now employed by or consult for the companies they recently regulated. This can create at least the appearance of conflicts of interest.In 2009, for example, an FDA panel weighed whether the agency should approve AstraZeneca’s widely prescribed antipsychotic drug quetiapine (Seroquel) for a wider range of conditions. The panel heard from health policy expert Wayne Ray of Vanderbilt University in Nashville, who described his research linking the drug to sudden cardiac death when used with certain other medications. Ray recalls “an FDA staff member who gave a very negative presentation on our paper.” And according to the meeting transcript, the agency’s then-Director of Psychiatric Products Thomas Laughren, who was instrumental in shepherding Seroquel and similar drugs through the review process and personally signed their FDA approvals, also challenged Ray’s results and defended AstraZeneca’s clinical trial findings in the discussion that followed. The company’s “analysis should have been able to pick up a difference in sudden cardiac death, and they didn’t find any difference between drug and placebo,” he said.Ray told Laughren and the panel that AstraZeneca had pooled data from all its trials as though the data were one data set, causing a well-known statistical error called Simpson’s paradox. To take the company’s conclusion “as definitive” would be “very dangerous,” Ray said, according to the transcript. Laughren responded by calling sudden death “a pretty definitive event.”center_img The Food and Drug Administration (FDA) says its rules, along with federal laws, stop employees from improperly cashing in on their government service. But how adequate are those revolving door controls? Science has found that much like outside advisers, regular employees at the agency, headquartered in Silver Spring, Maryland, often reap later rewards—jobs or consulting work—from the makers of the drugs they previously regulated.FDA staffers play a pivotal role in drug approvals, presenting evidence to the agency’s advisory panels and influencing or making approval decisions. They are free to move to jobs in pharma, and many do; in a 2016 study in The BMJ, researchers examined the job histories of 55 FDA staff who had conducted drug reviews over a 9-year period in the hematologyoncology field. They found that 15 of the 26 employees who left the agency later worked or consulted for the biopharmaceutical industry.FDA’s safeguards are supposed to keep the prospect of industry employment from affecting employees’ decisions while at the agency, and to discourage them from exploiting relationships with former colleagues after they depart. For example, former high-level employees can’t appear before the agency on the precise issues they regulated—sometimes permanently, in other cases for a year or two. By Charles PillerJul. 5, 2018 , 2:00 PM Sign up for our daily newsletter Get more great content like this delivered right to you! Country Click to view the privacy policy. Required fields are indicated by an asterisk (*) Ultimately, the committee voted overwhelmingly to advise approval of the drug for new indications and made no recommendation on labeling it to warn about sudden cardiac death. Later evidence showed that the cardiac problems Ray described are real, and in 2011, FDA required adding a warning on Seroquel’s label.Soon after, Laughren left the agency and formed a consultancy to help psychiatric drug makers, including AstraZeneca, navigate FDA approvals. He did not respond to repeated requests for comment.In 2012 and 2013, data expert Joan Buenconsejo led FDA’s analysis of medical statistics in drug reviews, including offerings from AstraZeneca. In 2014, she joined the company as a director and biometrics team leader. By 2015, Buenconsejo had already represented AstraZeneca before her former FDA colleagues as the company sought a drug’s approval. In an email, Buenconsejo wrote that she strictly adhered to FDA’s recusal rules “when considering employment with AstraZeneca.” She added, “I do not believe there was any conflict of interest around my transition.”Former FDA employees, AstraZeneca spokesperson Karen Birmingham wrote in an email, “bring the perspective of seasoned regulators” who can assist current regulators with the “challenging decisions in approving innovative medicines to meet unmet medical needs.”Jeffrey Siegel, who was an FDA staff member specializing in reviews for arthritis drugs, oversaw the 2010 approval of Genentech’s arthritis drug tocilizumab (Actemra). Months later, he left the agency to join the company and its parent, Roche, as director of the division that includes Actemra and related offerings. Siegel represented Roche before his former FDA colleagues when the company sought approval to promote Actemra for new conditions. Last year, he told STAT that the timing of his decision to join Roche and Genentech was coincidental.Laughren, Buenconsejo, and Siegel apparently complied with existing federal laws and FDA requirements. And David Kessler, who led FDA under former Presidents George H. W. Bush and Bill Clinton, says such moves to industry by former FDA experts, steeped in “a culture of drug regulation,” can benefit the public if they improve pharma practices. But “revolving door” rules need a fresh look, he adds, to ensure that “the tipping point, where that balance is,” serves the public interest.Vinay Prasad, a hematologist-oncologist at Oregon Health & Science University in Portland who co-wrote the 2016 study in The BMJ, contends that weak federal restrictions, plus an expectation of future employment, inevitably bias how FDA staffers conduct drug reviews.”When your No. 1, major employer after you leave your job is sitting across the table from you, you’re not going to be a hard-ass when you regulate. That’s just human nature.”*Correction, 10 July, 6:10 p.m.: An earlier version of this story stated that Thomas Laughren gave a negative presentation on Wayne Ray’s paper. He was among FDA staff who critiqued that work at the advisory meeting, but he did not give the detailed presentation.last_img read more

first_img Click to view the privacy policy. Required fields are indicated by an asterisk (*) N. Kashuba, et. al., bioRxiv 10.1101 (2018)/CC BY-NC-ND 4.0 Email Tarlike birch bark pitch from Sweden preserved both clear tooth impressions and DNA for thousands of years. Sign up for our daily newsletter Get more great content like this delivered right to you! Country This 8000-year-old ‘gum’ holds surprises about ancient toolmakerscenter_img Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe By Michael PriceDec. 10, 2018 , 11:30 AM Gum won’t really sit in your stomach for years, but it can preserve human DNA for millennia. Researchers have uncovered genetic material encased within 8000-year-old tarlike wads known as birch bark pitch, which Scandinavian hunter-gatherers chewed to make a glue for weapons and tools. Among other things, the DNA suggests these toolmakers were both male and female, and some may have been as young as 5 years old.“It’s exciting … that you could get DNA from something people chewed thousands of years ago,” says Lisa Matisoo-Smith, a molecular anthropologist at the University of Otago in Dunedin, New Zealand. “I think there are lots of ways people will take this going forward.”In the late 1980s, a team of Swedish archaeologists excavated a pit within an archaeological site called Huseby Klev in western Sweden. Here, they discovered more than 100 coal black, thumbprint-size lumps riddled with distinct toothmarks. Chemical analysis revealed these were pieces of pitch, an early adhesive derived from plant resin. Researchers already knew ancient toolmakers heated pitch distilled from birch trees over a fire to soften it, chewed bits of it into a pliable state, then used the sticky wad to fasten sharpened stones to wooden or bony shafts to make weapons and tools. Natalija Kashuba, an archaeology Ph.D. student at Uppsala University in Sweden, and colleagues wondered whether any usable DNA from the chewers’ saliva remained inside the hardened resin. Kashuba, who did the work while a student at the University of Oslo, and the rest of the team took tiny samples from three wads, ground them to powder, and put them through an extremely sensitive DNA amplification process designed to locate ancient DNA, which is often highly degraded.The researchers identified human DNA in all three pieces. Further analysis revealed each came from a different individual—two females and a male. Based on estimations of tooth size and wear taken from the toothmarks in the pitch, the researchers suspect the chewers were young, between 5 and 18 years old. Adult tooth impressions have also been found in pitch from the site, which could suggest an egalitarian toolmaking process involving all sexes and ages, the team reports this week on the bioRxiv preprint server.The DNA also revealed these pitch chewers belonged to a genetic group known as Scandinavian hunter-gatherers, who hunted reindeer in what are today Sweden and Norway some 8000 years ago. That confirms what anthropologists suspected, says Torsten Günther, an evolutionary biologist at Uppsala University who wasn’t involved in the work. The study’s real value, he says, is highlighting the promise of studying ancient human populations even when you can’t find the humans themselves. “Even if human remains are found, it would be an opportunity to perform these genomic studies without destructive sampling of those human remains.”Matisoo-Smith cautions that because the wads of pitch in the study weren’t found embedded in actual tools, we can’t be sure the chewers were toolmakers. They may have been children just chewing gum, she suggests. “Either way, it’s pretty cool.”last_img read more

first_img Mathieu Genest, the press secretary for Canada’s immigration minister in Ottawa, explained in an email that “Visa applications are assessed on a case-by-case basis. … Decisions are made by highly trained, independent visa officers.” Everyone gets evaluated on the same criteria, regardless of where they’re from, he added in an interview.The most common reason Canadian officials offered for denying a visa was that the applicant might not return home after the event, citing travel history, finances, or insufficient employment. In many cases, Canada also decided that letters of recommendation that Bengio had written for invitees were fraudulent, without explaining the reason or checking with Bengio.Bengio calls fears that foreign researchers would stay in Canada absurd. “Why would a Ph.D. student in Africa doing research in AI become an illegal immigrant in Canada and end up washing dishes and living undercover?” he says. “We all know that their skills are in high demand and that they’ll be able to get very good jobs almost anywhere.”Some NeurIPS invitees from Asia and Eastern Europe were also denied visas, Bengio says. But the high rejection and no-response rate for Africans—nearly 50%—“raise the possibility that bias, discrimination, and racism are part of the explanation.”The day before Black in AI, Canadian Prime Minister Justin Trudeau visited the headquarters of Element AI here—a company co-founded by Bengio—to announce an additional $230 million in federal funding for the field. When asked about the Black in AI visa issue, he told reporters someone would look into it.That pledge came too late for Mwiza Simbeye, a co-founder of AgriPredict, an app for identifying diseased crops, and a student at the African Leadership University in Kigali. He had won a Google fellowship and hoped to attend NeurIPS to meet his mentor. Coming from Rwanda, he was denied a visa twice, despite three recommendation letters—from NeurIPS, Google, and Black in AI.Canada also denied a visa to Tejumade Afonja, who co-organizes AI Saturdays Lagos, a study group in Nigeria, and works at InstaDeep, an AI company founded in Africa. She was invited to present work on ChowNet, a database of images of African food to help train image-recognition software. “I really felt so bad for not being able to attend,” Afonja says.NeurIPS will take place in Vancouver, Canada, in 2019 and 2020, but growing concern about visa issues means Canada risks losing other conferences. In 2020, to avoid visa issues, the International Conference on Learning Representations, a top AI conference co-founded by Bengio, will take place in Ethiopia.Timnit Gebru, a researcher at Google in Mountain View, California, and co-founder of Black in AI, says African scientists’ difficulty obtaining visas for Canada is “a long-standing problem” that demands attention. “This happens every day and no one cares,” Afonja says. “We are shedding more light on the process. 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Required fields are indicated by an asterisk (*) Sign up for our daily newsletter Get more great content like this delivered right to you! Country Black In AI MONTREAL, CANADA—Dozens of African researchers were denied visas for an artificial intelligence (AI) meeting here last week, even as the Canadian government takes steps to advance the country’s standing in AI and the field aims for greater inclusivity.Black in AI, a daylong workshop for scientists of African descent held in conjunction with the Conference on Neural Information Processing Systems (NeurIPS), a leading AI conference, had invited more than 200 scientists from Africa to participate. But about half of the visa applications led to denials or acceptances so delayed that the researchers were unable to attend. “It looks like we have some inconsistency between what one part of government does and what another does,” says Yoshua Bengio, a NeurIPS organizer and professor at the University of Montreal.NeurIPS is the largest AI conference in the world. This year, more than 8500 people came for academic talks, conversations with job recruiters, and social events. Conference organizers foresaw problems obtaining visas for foreign invitees and reached out to the Canadian government for help in July. Still, out of 230 Africans, about 15% heard back too late to attend or not at all. Another 33% were denied visas. Canada denied visas to dozens of Africans for a big artificial intelligence conferencelast_img read more

first_imgShareTweetSharePinDr. Worrel Sanford is the UWP candidate for the Kalinago ConstituencyUnited Workers Party (UWP) candidate for the Salybia constituency, Dermatologist, Dr. Worrel Sanford has stated that he is deeply appalled and worried by what he says is the blatant disrespect shown by the Ministry of Kalinago Affairs, the Ministry of Health and the government with regard to a human resource development activity which was recently undertaken in the Kalinago Territory.Dr Sanford has accused the named authorities of snubbing and undermining “the effort of one of their inspiring Kalinago women in taking the lead to contribute to the development of the human resource capital of the communities and more so, the empowering of  Kalinago women.”One of the graduates receives a trophySanford explained in a release that Anette Thomas-Sanford, a nurse by profession, recognizing the need for trained health care providers and the inability of the state mechanism to respond in a timely manner, conceptualized a health-care providers training programme with the input of the then Dean of Health Sciences at the Dominica State College (DSC), Denise Edwards. The course was offered in the Kalinago Territory.“Despite several attempts to engage the Ministry of Health and Kalinago Affairs, they made absolutely no effort to get involved, to advice, support or to endorse the programme,” Sanford stated. “Not even the Salybia Health Center; the state did not spend one cent in constructing, did they want to make available for the six (6) month programme.”He continued, “Thanks to the Kalinago Chief for his tenacity! At the end, 18 young women graduated from the programme despite the calculated barriers set by the very same people who profess on political platforms and selected forums that they are pro-women independence and people empowerment and no one loves the Kalinago people more than they do.”Sanford contends that one is left with no choice but to “discard in the trash bins, the pronouncements made by some of us in leadership positions as it relates to the socio-economic development of our people and in particular our indigenous Kalinago women.” He said as a medical professional, he fully endorsed “this outstanding initiative” by Nurse Thomas-Sanford and vowed, under a UWP led government, to explore all possible avenues for the further development of this programme, given its dire need.“The double standard, snubbing and politicizing of all good efforts by our people cannot continue to go unabated if we truly want to see a better society tomorrow,” he remarked. “Such calculated actions are tantamount to building walls and not bridges.”Sanford insists that the Ministry of Kalinago Affairs must be and will be run as a state entity which facilitates the development of the Kalinago people not as a DLP outpost, “with a sole mandate to thwart the progress of our communities by keeping our people in a state of perpetual dependence.” He strongly denounced what he described as “pathetic, short sighted and irresponsible approach to the betterment of our people at a time when our communities and nation need us more than ever.”He congratulated Thomas-Sanford on her “bold” initiative as well as the course participants who despite the odds, completed the programme.Certification will be done by the Caribbean Association of National Training Agencies and participants will receive a Caribbean Vocational Qualification certificate (CVQ) to be issued by the Grenada National Training Authority ably facilitated by Abraham Durand.Some smiling faces at the graduation ceremonylast_img read more