first_imgMovie and TV streaming service Wuaki.tv has launched a new app that will make it available on Windows 8.1 PCs, laptops and tablets for the first time. The free app was developed in partnership with Microsoft, and is available from today.“At Wuaki.tv, we are committed to providing the best possible user experience and HD quality plays an important role within that. Our users are increasingly used to seeing the latest movies in high definition on their Smart TVs, consoles, and other devices, and now they can add their PC or laptop to this list too,” said Wuaki.tv founder and CEO, Jacinto Roca.last_img read more

first_imgIt states that police have submitted a file on an additional suspect who has been reported to the PPS by the PSNI.The letter says: “The suspect is not a soldier and is not alleged to have shot any civilian. The file relates to alleged Official IRA activity on Bloody Sunday.”In 1969, the IRA split into the Official IRA and the Provisional IRA.The Bloody Sunday Inquiry, led by English judge Lord Saville, was the longest and most expensive in UK history.During the inquiry, former members of the Official IRA – giving evidence anonymously – said the organisation had shot at soldiers very early on in retaliation for the shooting of two of the protesters.They denied that the organisation had fired first on Bloody Sunday.The letter from the PPS reveals that the republican suspect under consideration, will be subject to the same test for prosecution as the soldiers.It also states that they understand that the police are preparing another file on a second person over the activities of the Official IRA, and that file will be based on statements due to be made by some people who have previously not given statements to the PSNI.The PPS is also examining eight further files on Bloody Sunday but adds that the file on the Official IRA suspect is brief and should not take a great deal of time to consider.But, overall, the introduction of the new material will mean that they will not be able to move towards a decision for another six months.A spokesperson for the PPS told BBC Radio Foyle that they have provided regular updates to all the families over the Bloody Sunday case and the PSNI, in the last year, provided about 35 files of material.The PPS added that its focus is on completing examination of those files and all relevant legal issues.It confirmed that one further suspect has been added and another report is expected. But, they don’t believe this will add significantly to the timescale for their decision.The Ministry of Defence said that due to ongoing legal proceedings it was inappropriate to comment.The PSNI confirmed it had sent a number of files to the PPS.OFFICIAL IRA MEN MAY FACE PROSECUTION OVER BLOODY SUNDAY was last modified: September 29th, 2017 by John2John2 Tags: THE Public Prosecution Service is considering bringing charges against former members of the Official IRA for their role in the events of Bloody Sunday.The PSNI has forwarded a file to the Public Prosecution Service (PPS) on one former IRA member and is understood to be preparing a file on a second.Thirteen people were shot dead when the Army’s Parachute Regiment opened fire on civil rights demonstrators in 1972. ShareTweet LORD SAVILLEOFFICIAL IRA MEN MAY FACE PROSECUTION OVER BLOODY SUNDAYPPSPSNI Another died of his injuries some months later.The details have emerged in a letter sent by the PPS to relatives of Bloody Sunday victims on 19 September.It outlines why it will take at least another six months to come to a decision on whether or not to bring possible charges, including murder against former members of the British Parachute Regiment.But the possibility of prosecutions against republicans for their activity on the day has also been raised.last_img read more

first_img – NEW WARNING FROM DOUG CASEY – READ IMMEDIATELY Over the years, Doug Casey’s forecasts have caused a lot of controversy… Like during the peak of the dot-com bubble when he warned a major crash in tech stocks was near… Or near 2008 when he warned America’s financial structure would be threatened with collapse. Critics called him “offensive,” “brash,” “irreverent.” But Doug was spot-on, every time. Not only that… Folks who heeded his warnings had the opportunity to make rare and extraordinary gains of 770%, 1,333%, and more. Yet, those could be a drop in the bucket if his latest controversial forecast about President Trump is right. Click here for the full story. Recommended Links — WARNING: Don’t File Social Security Benefits Until You See This We just uncovered something shocking that could mean the difference between collecting a meager $1,000 from Social Security… Or getting up to $6,235 a month you can use for your retirement. That’s real cash deposited in your account… coming from the private sector. But according to a law that governs this special situation, you must act before April 21. Click here to get started today. Editor’s note: The “Greater Depression” has started… Yesterday, Casey Research founder Doug Casey compared what happened in the 1930s to what’s going on today. Below, he breaks down more of these likely differences… By Doug Casey, founder, Casey Research PRICES 1930s Prices dropped radically because billions of dollars of inflationary currency were wiped out through the stock market crash, bond defaults, and bank failures. The government, however, somehow equated the high prices of the inflationary ’20s with prosperity and attempted to prevent a fall in prices by such things as slaughtering livestock, dumping milk in the gutter, and enacting price supports. Since the collapse wiped out money faster than it could be created, the government felt the destruction of real wealth was a more effective way to raise prices. In other words, if you can’t increase the supply of money, decrease the supply of goods. Nonetheless, the 1930s depression was a deflationary collapse, a time when currency became worth more and prices dropped. This is probably the most confusing thing to most Americans since they assume—as a result of that experience—that “depression” means “deflation.” It’s also perhaps the biggest single difference between this depression and the last one. Today Prices could drop, as they did the last time, but the amount of power the government now has over the economy is far greater than what was the case 80 years ago. Instead of letting the economy cleanse itself by allowing the financial markets to collapse, governments will probably bail out insolvent banks, create mortgages wholesale to prop up real estate, and central banks will buy bonds to keep their prices from plummeting. All of these actions mean that the total money supply will grow enormously. Trillions will be created to avoid deflation. If you find men selling apples on street corners, it won’t be for 5 cents apiece, but $5 apiece. But there won’t be a lot of apple sellers because of welfare, nor will there be a lot of apples because of price controls. Consumer prices will probably skyrocket as a result, and the country will have an inflationary depression. Unlike the 1930s, when people who held dollars were king, by the end of the Greater Depression, people with dollars will be wiped out. THE SOCIETY 1930s The world was largely rural or small-town. Communications were slow, but people tended to trust the media. The government exercised considerable moral suasion, and people tended to support it. The business of the country was business, as Calvin Coolidge said, and men who created wealth were esteemed. All told, if you were going to have a depression, it was a rather stable environment for it; despite that, however, there were still plenty of riots, marches, and general disorder. Today The country is now urban and suburban, and although communications are rapid, there’s little interpersonal contact. The media are suspect. The government is seen more as an adversary or an imperial ruler than an arbitrator accepted by a consensus of concerned citizens. Businessmen are viewed as unscrupulous predators who take advantage of anyone weak enough to be exploited. A major financial smashup in today’s atmosphere could do a lot more than wipe out a few naives in the stock market and unemploy some workers, as occurred in the ’30s; some sectors of society are now time bombs. It’s hard to say, for instance, what third- and fourth-generation welfare recipients are going to do when the going gets really tough. THE WAY PEOPLE WORK 1930s Relatively slow transportation and communication localized economic conditions. The U.S. itself was somewhat insulated from the rest of the world, and parts of the U.S. were fairly self-contained. Workers were mostly involved in basic agriculture and industry, creating widgets and other tangible items. There wasn’t a great deal of specialization, and that made it easier for someone to move laterally from one occupation into the next, without extensive retraining, since people were more able to produce the basics of life on their own. Most women never joined the workforce, and the wife in a marriage acted as a “backup” system should the husband lose his job. Today The whole world is interdependent, and a war in the Middle East or a revolution in Africa can have a direct and immediate effect on a barber in Chicago or Krakow. Since the whole economy is centrally controlled from Washington, a mistake there can be a national disaster. People generally aren’t in a position to roll with the punches as more than half the people in the country belong to what is known as the “service economy.” That means, in most cases, they’re better equipped to shuffle papers than make widgets. Even “necessary” services are often terminated when times get hard. Specialization is part of what an advanced industrial economy is all about, but if the economic order changes radically, it can prove a liability. THE FINANCIAL MARKETS 1930s The last depression is identified with the collapse of the stock market, which lost over 90% of its value from 1929 to 1933. A secure bond was the best possible investment as interest rates dropped radically. Commodities plummeted, reducing millions of farmers to near subsistence levels. Since most real estate was owned outright and taxes were low, a drop in price didn’t make a lot of difference unless you had to sell. Land prices plummeted, but since people bought it to use, not unload to a greater fool, they didn’t usually have to sell. Today This time, stocks—and especially commodities—are likely to explode on the upside as people panic into them to get out of depreciating dollars in general and bonds in particular. Real estate will be—next to bonds—the most devastated single area of the economy because no one will lend money long term. And real estate is built on the mortgage market, which will vanish. Everybody who invests in this depression thinking that it will turn out like the last one will be very unhappy with the results. Being aware of the differences between the last depression and this one makes it a lot easier to position yourself to minimize losses and maximize profits. So much for the differences. The crucial, obvious, and most important similarity, however, is that most people’s standard of living will fall dramatically. The Greater Depression has started. Most people don’t know it because they can neither confront the thought nor understand the differences between this one and the last. As a climax approaches, many of the things that you’ve built your life around in the past are going to change and change radically. The ability to adjust to new conditions is the sign of a psychologically healthy person. Look for the opportunity side of the crisis. The Chinese symbol for “crisis” is a combination of two other symbols—one for danger and one for opportunity. The dangers that society will face in the years ahead are regrettable, but there’s no point in allowing anxiety, frustration, or apathy to overcome you. Face the future with courage, curiosity, and optimism rather than fear. You can be a winner, and if you plan carefully, you will be. The great period of change will give you a chance to regain control of your destiny. And that in itself is the single most important thing in life. This depression can give you that opportunity; it’s one of the many ways the Greater Depression can be a very good thing for both you as an individual and society as a whole. Editor’s note: America is about to enter a crisis far more severe than what we saw in 2008–2009. It could all start after Trump’s inauguration and could change everything… in sudden, unexpected ways. This is exactly why Doug and his team put together a time-sensitive video explaining how it could all go down. Click here to watch it now.last_img read more

first_img[dropcap]P[/dropcap]erhaps if teams are so lethargic about the FA Cup then they should just not enter the competition ?It’s a sad state of affairs – perhaps the glory FA Cup days are gone forever?West Ham got what they deserved earlier today when their ‘junior’ side were brushed aside by Nottingham Forest – just as the Star Sports market indicated.Punters only wanted to be with Forest after the line-ups were made public and were rewarded with a 5-0 win.For Man U, the FA Cup is considered only their ‘third priority’ of the season behind the Premier and Champions League. So how can you possibly lump on at short odds with that news combined with the fact that they have some high profile absentees.Rooney (groin) and Van Persie (thigh) are both injured, as is winger Ashley Young (shoulder).United have not won the FA Cup since 2004, when they beat Millwall in the final and face Swansea today in a re-run of the match that gave David Moyes his first success as United manager in August.HEAD TO HEAD RECORD(Max last 10 only)Aug 2013 Premier Swansea 1-4 Man UtdMay 2013 Premier Man Utd 2-1 SwanseaDec 2012 Premier Swansea 1-1 Man UtdMay 2012 Premier Man Utd 2-0 SwanseaNov 2011 Premier Swansea 0-1 Man UtdMay 1983 Div 1 (old) Man Utd 2-1 SwanseaDec 1982 Div 1 (old) Swansea 0-0 Man UtdJan 1982 Div 1 (old) Swansea 2-0 Man UtdSep 1981 Div 1 (old) Man Utd 1-0 SwanseaApr 1938 Div 2 (old) Swansea 2-2 Man UtdThe problem you have if you are considering opposing Man U is that Swansea arrive here in a slump. They are 13th in the table and if their recent form continues then they will very much be in the relegation battle.Swansea have never won at Old Trafford and come into the tie on the back of seven games (in all competitions) without a victory.Hopefully though the FA Cup still means enough to them against a below strength Man U side and I’m taking a chance with the draw at around 7/2.RECOMMENDED BET (1-10 points)5 points DRAW at around 7/2 with Star SportsRUNNING RETURN (JANUARY): -15.00 POINTSWhat’s your view? CALL STAR SPORTS 08000 521 321last_img read more

first_imgCheck Out Some New MBA Jobs at These Global Finance Firms About the AuthorMax PulciniMax Pulcini is a Philadelphia-based writer and reporter. He has an affinity for Philly sports teams, Super Smash Bros. and cured meats and cheeses. Max has written for Philadelphia-based publications such as Spirit News, Philadelphia City Paper, and Billy Penn, as well as national news outlets like The Daily Beast.View more posts by Max Pulcini One of the most lucrative careers an MBA can pursue is in financial services. Newer MBA jobs in this field include risk management specialists, financial analysts and asset managers, as well as roles in related emerging sub-sectors like FinTech. For MBAs looking to break into this field, check out our list of five exciting new MBA jobs at these top financial services firms:Product Manager – Capital OneCapital One Financial Corporation is a bank holding company specializing in credit cards, auto loans, banking, and savings accounts. The firm calls McLean, Virginia its home and is a recruiter of top MBA talent. Capital One is hiring a Product Manager to work in Enterprise Customer Intelligence at the company’s New York City office. The Enterprise Customer Intelligence team develop APIs, data platforms, and tools for Capital One to develop and apply continuous customer understanding for all consumer products and experiences.The new Product Manager will be expected to deliver data capabilities, platform services and tools that enable developers and analysts to utilize customer context when building customer centric products that solve business problems. The role requires at least three years of experience in digital product management, and is MBA preferred. Additional activities of the Product Manager include:Developing new data capabilities aimed at delivering customer understanding, context and eventsPrioritizing business roadmap against needs, long-term platform health and partnership needsOverseeing and coordinating delivery of API and platform toolsEvangelizing platform capabilities with the consumersCollaborating with partner teams to inform end customer experiencesYou can visit the company career site to see more Capital One finance jobs.Senior Risk Manager – FidelityFidelity Investments Inc. is a financial services corporation based in Boston, managing a reported $2.5 trillion worth of assets. The company is an active MBA recruiter, and has opportunities in technology, finance, investment, or business strategy for MBAs and MBA graduates. Fidelity is hiring a new Senior Risk Manager at its Boston office. The new hire will join the Corporate Risk team, and be responsible for managing Fidelity’s Model Governance and Counterparty Risk. New hires require a minimum of five years of experience in financial services and an MBA degree.Roles of the Senior Risk Manager include:Supporting and managing model risk reportingTraining on policy, standards and proceduresMeasuring and reporting risk and limits and enhance tools and reports related to credit and market risksEstablishing relationships with the lines of business, model validation teams, and risk management staffSupporting ad-hoc report requests for analysis and/or researchSee this job, and many more, at the Fidelity careers page.Senior Financial Analyst – VisaVisa Inc., headquartered in Foster City, CA, is one of the most recognizable companies in the world, facilitating electronic funds transfers through Visa-branded credit, gift, and debit cards. Visa is currently seeking out MBA graduates and current students, placing them in marketing, product, finance, and strategy roles.Visa is looking for MBAs to join its Senior Financial Analyst MBA program. This full-time program out of Visa’s Foster City, CA and San Francisco offices provides the opportunity to work in different areas in Visa for six months at a time. For consideration, candidates must have an MBA from a leading business school with an anticipated graduation date in early 2019. In addition, potential candidates should have three to five years of relevant financial analysis work experience.New hires will get to work in the following areas of Visa’s business:Financial Planning & Analytics: Partnering with businesses to develop budgets, forecasts and investment strategiesControllership: Assisting with accounting transactions, issuing financial filings and financial statements, and managing Visa’s compliance financial internal controls programClient Incentives: Collaborating with stakeholders to identify client opportunities that achieve strategic and financial goalsSourcing: Supporting cost-effective procurement of goods and services, while minimizing riskTreasury: Managing corporate cash and investment portfolios, foreign exchange exposure and rate setting, capital and debt strategy, liquidity management, settlement and insurance programsVisit the Visa careers page to see more job openings.Investment Bank Business Analyst – UBSUBS Group AG is a Swiss multinational investment bank and financial services company, operating globally. Stateside, UBS is hiring a new Investment Bank Business Analyst to join its Corporate Client Solutions (CCS) team in New York. This team is responsible for strategic business planning, maintaining the control environment, and driving business initiatives. UBS is looking for candidates with investment banking, accounting, or management consulting experience. An MBA degree is preferred.Major of the Investment Bank Business Analyst responsibilities include:Driving innovation and digitization through the CCS Innovation programSupport CCS Senior Management with cost management and strategic initiativesCoordinate regulatory inquiries and regulatory driven change programsAssist on ad hoc projectsSee more jobs like this at UBS’ careers page.Americas Treasury Coverage Analyst – Credit SuisseJust like UBS, Credit Suisse Group AG is another Swiss investment bank and financial services company looking for new MBA talent.YOU MAY ALSO LIKE: Top MBA Recruiters: Credit SuisseCredit Suisse is hiring an Americas Treasury Coverage Analyst to join the firm’s Raleigh, NC office. This is an especially exciting opportunity given Credit Suisse’s commitment to the area, significantly expanding its Raleigh employee base over the past two years, making it the primary corporate and business support location for the firm’s U.S. businesses. Candidates should have two or more years working experience in international banking or financial services, and an MBA is preferred.Job responsibilities of the Americas Treasury Coverage Analyst include:Participating in Treasury’s Global New Business processOrganize responses and workflows regarding Recovery and Resolution PlanningBuilding in-depth analysis and presentations for senior management discussionsLeading the process around internal governance meetingsProviding ad hoc analysts when requiredCredit Suisse posts this job, and many others, on its careers page. Relatedcenter_img Last Updated Jan 30, 2019 by Max PulciniFacebookTwitterLinkedinemail regions: Atlanta / Baltimore / Boston / Chicago / Dallas / Denver / Houston / London / Los Angeles / Miami / New York City / Online / Philadelphia / Research Triangle / San Diego / San Francisco / Seattle / Toronto / Washington, DClast_img read more

first_img Staff Writer. Covers leadership, media, technology and culture. The only list that measures privately-held company performance across multiple dimensions—not just revenue. This article is included in Entrepreneur Voices on Company Culture, a new book containing insights from more than 20 contributors, entrepreneurs, and thought leaders.During a Tuesday meeting to discuss an overhaul of Uber’s company culture, former board member David Bonderman proved exactly why the conversations needed to happen in the first place.At the start of the all-hands meeting, Arianna Huffington, who was the first woman to join the company’s board last year, announced the addition of Nestlé executive Wan Ling Martello to the board, increasing the representation of women on the board from 14 to 25 percent.“There’s a lot of data that shows when there’s one woman on the board, it’s much more likely that there will be a second woman on the board,” Huffington noted.That’s when Bonderman interrupted.“Actually what it shows is it’s much likely to be more talking.”In the recording obtained by Yahoo Finance, you can hear Huffington respond at first with awkward laughter. And then her reply: “Oh. Come on, David. Don’t worry, David will have a lot more talking to do as well.”That is not to be the case, as Bonderman resigned shortly after the meeting, which, it bears repeating, was convened to talk about recommendations to change Uber’s culture after allegations of systemic discrimination and sexual harassment.Related: 3 Lessons Every CEO Can Learn From Travis Kalanick’s Emotional Meeting With Uber’s Female EngineersBonderman, the 74-year-old founding partner of investment firm TPG Capital, apologized for the “disrespectful” comment via an internal memo to Uber employees and issued this statement about his departure:”I do not want my comments to create distraction as Uber works to build a culture of which we can be proud. I need to hold myself to the same standards that we’re asking Uber to adopt. Therefore, I have decided to resign from Uber’s board of directors, effective tomorrow morning.”Earlier on Tuesday, CEO Travis Kalanick also announced that he would be taking a leave of absence in order to, as he shared in an email to the company, “take some time off of the day-to-day to grieve my mother, whom I buried on Friday, to reflect, to work on myself, and to focus on building out a world-class leadership team. The ultimate responsibility, for where we’ve gotten and how we’ve gotten here rests on my shoulders,” Kalanick wrote. “There is of course much to be proud of but there is much to improve. For Uber 2.0 to succeed there is nothing more important than dedicating my time to building out the leadership team. But if we are going to work on Uber 2.0, I also need to work on Travis 2.0 to become the leader that this company needs and that you deserve.”Related: Travis Kalanick to Take a Leave of Absence. Here Are 9 CEOs Who Were Fired or Decided to Step Down.So what exactly is Uber 2.0 going to look like?Over the past few months, former attorney general Eric Holder and Tammy Albarrán, partners at law firm Covington & Burling, were tasked with investigating the allegations made by former engineer Susan Fowler and others.They interviewed more than 200 Uber employees and provided a set of recommendations pertaining to how the company should address discrimination, harassment and retaliation and how it could “ensure that its commitment to a diverse and inclusive workplace was reflected not only in the company’s policies but made real in the experiences of each of Uber’s employees.”The recommendations include:Providing more support for the human resources department and establishing clear protocols to track complaints.Mandatory training for senior executives, HR staffers, managers and people in the position to interview prospective employees, particularly around the topics of promoting inclusion and combatting unconscious bias.In terms of recruiting and developing talent, implementing a blind resume review, and increased transparency when it comes to performance reviews and promotions.The prohibition of romantic or intimate relationships between supervisor/subordinates and the consumption of alcohol during work hours, at after work events and at company-sponsored events.An update of discrimination and harassment policies including instituting a zero-tolerance policy for violators of those rules — no matter what position they hold in the company — and explicit protection against harassment from not only other employees, but third-parties the company deals with such as clients to vendors.Related: A 2013 Letter From Uber’s Travis Kalanick Lays Out Sex Rules for Employees at Company PartyA lot of these seem quite standard. But when you look at former engineer Susan Fowler’s blog post and Kalanick’s 2013 Miami letter side by side, the necessity for Holder and Albarrán to explicitly state things such as the importance of “de-emphasizing alcohol as a component of work events,” or that policies should be applied consistently across the company with no special treatment afforded to any one employee is pretty glaring.One passage in particular about Uber’s 14 cultural values speaks volumes about where Uber ran aground. Holder and Albarrán recommended that the company communicate with its employees to reassess and develop a core list of values that are accessible and easy to understand.  “Eliminate those values which have been identified as redundant or as having been used to justify poor behavior, including Let Builders Build, Always Be Hustlin’, Meritocracy and Toe-Stepping, and Principled Confrontation; and encourage senior leaders to exhibit the values on a daily basis and to model a more collaborative and inclusive Uber culture,” the recommendation reads. “Leaders who embody these values should be part of the process of redefining Uber’s values and should be role models for other leaders within the company.”Related: Uber CEO Travis Kalanick Says He Needs to ‘Grow Up’ After Video of Argument With a Driver ReleasedUber has long had a reputation for aggressive tactics in its dealings with regulators and competitors. It was seen, for better or worse, as one of the key drivers of its rapid growth. But clearly, as Uber’s experience shows us, growth and success are not one in the same.In an interview with Vanity Fair in 2014, Kara Swisher asked Kalanick about the nature of the interactions with the leaders of the cities (some of whom he described as “really awesome, but most are uninspired”) his business was disrupting.“If you don’t agree with the core principles, which are the premise of that compromise, then you have to have what I call principled confrontation. And so that is the thing that we do that I think can rub some people the wrong way.”If you’re beginning with the premise that compromise doesn’t work for you, and every interaction is a war of attrition, you can let people build all they want, but what exactly are you working toward?If you’re always hustlin’ — though if they do keep that one, I would urge them to restore the “g” to its rightful place — you don’t stop to think about where the pitfalls may be or whether you might be in the wrong. Uber’s experience shows us that is kind of approach is a recipe for collapsing under the weight of your own hubris.Related: If Elon Musk Can Admit His Mistakes, Then So Can YouIn Uber’s San Francisco headquarters, up until this week, the office’s main conference room was called aptly, the War Room. Bloomberg reported that along with the multitude of changes recommended by Covington & Burling, the room is now going to be called the Peace Room. It’s a bit on nose, but you can appreciate the thought, as long as it’s not just lip service.Uber’s culture is not going to change overnight, but now the company seems to have the self-awareness and tools in place to build an environment where values aren’t used, as per Holder and Albarrán’s description, to “justify poor behavior.”So what can we learn from Uber’s newfound emphasis on internal, rather than external growth? Company culture isn’t about perks or empty aphorisms that look good on a T-shirt. Simply, people want to be heard, they want their work to be valued and they want to be treated with respect. When you build your company culture, start there. Entrepreneur Staff 82shares Nina Zipkin Image credit: Spencer Platt | Getty Images 2019 Entrepreneur 360 List Apply Now »center_img Uber June 15, 2017 Uber Needs to Recreate its Company Culture. Here’s What You Can Learn From Its Mistakes. Add to Queue Start by treating people with respect. It’s as simple as that. 8 min read Next Article last_img read more

first_img Next Article February 12, 2009 Technology The only list that measures privately-held company performance across multiple dimensions—not just revenue. Ustream.TVFounders/ages: Gyula Feher, 30; John Ham, 30; Brad Hunstable, 30Launched: 2007App: A destination platform for streaming live video over the internet; includes co-hosting, chat and hyperlink overlay functionsWhy it works: While YouTube hosts previously recorded videos, Ustream hosts live content, allowing real-time viewing and interaction.Just UptimeFounder/age: Chris Phillips, 25Launched: June 2008App: A website- and server-monitoring application that provides instant e-mail notifications, SMS text alerts and detailed reporting when your website or server is downWhy it works: Sure, a few people out there spend every waking moment online. But for those who don’t, this intuitive app gives them a heads up when issues arise.OoVooCEO/age: Philippe Schwartz, 44Launched: 2007App: An innovative video service for creating video messages, real-time video chats for up to six people and live video callsWhy it works: Communication, whether between friends and family or employees and business partners, has moved online. OoVoo allows face-to-face conversations when being in the same room isn’t possible. Lindsay Holloway Apply Now » This story appears in the March 2009 issue of Entrepreneur. Subscribe » If you’re thinking about creating a web app–whether as a business or to use in your existing business–its construction costs and time can run the gamut. It depends on many factors: how complicated the technology is, what tools you use to build it and so on. But details aside, here are a few web app entrepreneurs who show us it can be done.Iotum CalliflowerFounders/ages: Alec Saunders, 45; Howard Thaw, 52Launched: June 2008App: A meeting tool that bridges businesses and social networks to allow the planning of and participation in interactive conference callsWhy it works: The solution is all-encompassing: It combines high-quality audio conferencing, scheduling, file sharing and collaboration in an easy-to-use interface.MedAppsFounder/age: Kent E. Dicks, 48Launched: 2005App: A two-part application that provides a remote health-monitoring solution; the mobile app collects patient data and readings that a health-care professional monitors via the web appWhy it works: MedApps makes remote health monitoring accessible and inexpensive to the more than 133 million people in the U.S. with at least one chronic condition. Magazine Contributor Yes, You Can Build Your Own Web App 2019 Entrepreneur 360 List Get started nowInspired to build your own web app? These sites can help you take that first step. –shares 2 min read Add to Queue Caspio Coghead Intuit QuickBase Zoho Creatorlast_img read more

first_img Your reaction to particularly awful days can make or break future success. The better action to take is to remain as calm as possible. Take quiet time to analyze how far you have come. Think about the twists and turns, and what currently has you stopped in your tracks.Numerous conversations revealed that many almost quit their current endeavors. But one common factor as to why they did not quit helped them to prevail: They enjoy what they do too much! Ironically, it has become their way of life.As uncertainty hits, follow these two suggestions:Take the time needed to uncover the better route.Convert a negative frame of mind into a positive.Reframe the situationOne sales technique referred to as “Reframing” applies very well to difficult situations. Whether personal or trying to work with a client, the first step is to figure out where the discontent originates. Upon recognizing the misstep, it becomes easier to work together to find the better solution. By asking a series of questions such as, “What if…” the improved path begins to reveal itself.On the personal side, moving from negative to positive thought is the beginning step for improvement. The change in attitude makes an enormous difference in providing increased opportunity to save the day.The day that you find you are doubting yourself, take private time to consider “the why” that is. Most likely, one of your peers will have had a similar experience. Have a conversation about how they dealt with it and ask for recommendations on how to handle. Their insights won’t necessarily apply or even matter. It’s more about the conversation itself. Just by unleashing the dilemma is all it takes to get back to full steam ahead.  As others see you meeting negativity and obstacles head on, they come to admire your steadfast personal brand.Tips:When negativity hits, stop to examine the origin.Decide whether changes need to be made.Should changes be in order, decide whether they are minor or major.Begin the process by eliminating the no longer needed.Create a list of what needs to be fixed.Prioritize the list in order of immediate need.Re-energize yourself and/or business by communicating. –shares Image credit: Shutterstock Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. The day that you find you are doubting yourself, take private time to consider why that is. Elinor Stutz Opportunity CEO of Smooth Sale, Author & Inspirational Speakercenter_img September 17, 2016 Next Article Add to Queue 2 min read This story originally appeared on Personal Branding Blog Transform Dark Days into Opportunity Enroll Now for $5last_img read more

first_imgUnstoppable Domains, a software company building domains on blockchains, today announced which 60 .zil domains it will auction on June 27. These domains represent the top 60 most watched Zilliqa domain names on the Unstoppable Domains website. The top domain, bitcoin.zil, has already attracted 505 potential buyers.“We are excited to see growing enthusiasm for blockchain domains,” said Matthew Gould, Unstoppable Domains CEO. “These domains provide two very critical benefits to users: they enable people to send crypto to a single human readable name, and they offer a platform to create uncensorable websites. The concepts of free speech and growing the crypto community are really resonating with our customer base.”Marketing Technology News: Triton Digital Integrates Centro’s Basis Platform with the a2x Programmatic Marketplace.Zil domains have seen high demand over the past 3 months, even though top domains have yet to be released. Users can, however, watchlist the domains they are most interested in bidding on during the coming public auction. Here are the top 60 most watchlisted domains:Which domains will be up for auction?1. bitcoin2. crypto3. porn4. blockchain5. money6. insurance7. gold8. cars9. hotels10. satoshi11. bra12. zil13. usa14. bank15. wallet16. beer17. ethereum18. carinsurance19. lasvegas20. pay21. trump22. weed23. travel24. toys25. pizza26. cannabis27. xxx28. litecoin29. privatejet30. music31. xrp32. fb33. z34. shop35. 36036. coffee37. coin38. cash39. vacationrentals40. porno41. hotel42. payme43. booking44. diamond45. insure46. game47. exchange48. 149. ripple50. donaldtrump51. abc52. cardano53. auction54. shoes55. ai56. car57. we58. domain59. elonmusk60. israelThe auction will be split into two phases. During phase I, the 60 most watchlisted domains will be available for a buy now price of $10,000 each. Domains can be purchased using bitcoin, ethereum, litecoin, and bitcoin cash.Marketing Technology News: Mindtree to Showcase Contextual, Real-Time Solutions for Personalized Traveler Experiences at HITEC MinneapolisDuring phase II, domains can only be purchased with Zilliqa.Bidding will start between $10 and $1,000 depending on the price of the domain in the pre-order phase. Each subsequent bid must be at least 5 percent greater than the previous bid. If a person is outbid, they will immediately get their funds returned. New bids will add additional time (~1 hour) to the auction to prevent auction sniping. Also, bidding will be capped at $10,000 per domain. Anyone in the world can participate and anyone in the world can watch the auctions as they happen.Marketing Technology News: CoreMedia Announces CoreMedia Content Cloud – Marketing Connector on Salesforce AppExchange, the World’s Leading Enterprise Cloud Marketplace Marketing TechnologyMatthew GouldNewsUnstoppable DomainsZilliqa Domain Previous ArticleMarTech Interview with Duncan Stockdill, Co-Founder and CEO at CapsuleNext ArticleFranklin Sports Selects CommerceIQ To Empower Their E-Commerce Team To Manage Amazon Holistically Unstoppable Domains Announces the Top 60 Zilliqa Domain Names Up for Auction Business WireJune 19, 2019, 1:45 pmJune 19, 2019 last_img read more

first_imgReviewed by James Ives, M.Psych. (Editor)Mar 20 2019Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher.The findings, published in the Journal of Clinical Oncology, could help define strategies to more effectively treat colorectal cancer, the second leading cause of cancer death in the United States.”This is an example of precision oncology, where using genetics, we are able to stratify tumor types that we once believed were homogeneous, and to identify new patient subgroups that might benefit from tailored therapies,” said UNC Lineberger’s Federico Innocenti, MD, PhD, associate professor in the UNC Eshelman School of Pharmacy Division of Pharmacotherapy and Experimental Therapeutics.For the study, researchers analyzed mutations in tumors of 843 patients who participated in a phase III clinical trial. The trial compared treatment with chemotherapy plus either bevacizumab or cetuximab – regimens which are now the standard of care for this disease in the advanced stage. The researchers used tumor samples to analyze genetic mutations in the DNA. Then, they examined associations between the mutations and data on patients’ responses to the treatments and survival.One key finding from the analysis was that patients who had a lot of genetic repeats in their tumor DNA – known as microsatellite instability – had longer survival when treated with bevacizumab compared to patients treated with cetuximab.”This finding has important potential implications for treatment of patients with microsatellite instability – a subgroup that represented about 7 percent of patients in our study,” Innocenti said.Related StoriesSugary drinks linked to cancer finds studyBacteria in the birth canal linked to lower risk of ovarian cancerStudy reveals link between inflammatory diet and colorectal cancer riskAnother key finding was that patients with tumors that had more genetic variation, which they called high tumor mutational burden, lived longer than patients who had tumors with less variation. The level of tumor mutational burden defines a new subgroup of patients with better prognosis, Innocenti reported.Studies are ongoing in Innocenti’s lab to try to understand the role of the body’s immune system in contributing to the finding. Researchers want to know if these patients with higher tumor mutational burden will be more responsive to treatments that work by unlocking the immune system against cancer.”It is crucial to define which patients could be responsive to immunotherapy in this setting, and this study shows the first promising evidence to do so,” Innocenti said.The study also confirmed findings previously made for patients who had mutations in the BRAF gene in their tumors. They found these patients had worse survival compared to patients who didn’t. Median survival for patients with the mutation was 13.5 months, compared to 30.6 months in patients without mutations.”This mutation was a very strong negative prognostic factor,” Innocenti said. “There was a clear difference in survival.”There was no difference in the study between the different treatment strategies studied in the trial for patients with or without the BRAF mutation. However, Innocenti said the finding confirms these tumors have a different biology and should be treated differently.Additional studies are needed to evaluate and confirm findings with therapeutic implications in patients, Innocenti said. Further research is planned to study additional ways of stratifying patients based on their genetic features to improve outcomes. Source:https://unclineberger.org/news/precision-oncology-insights-revealed-for-colorectal-cancer/last_img read more

first_img Source:https://news.illinois.edu/view/6367/775169 Reviewed by James Ives, M.Psych. (Editor)Apr 17 2019Oxidants found within living organisms are byproducts of metabolism and are essential to wound-healing and immunity. However, when their concentrations become too high, inflammation and tissue damage can occur. University of Illinois engineers have developed and tested a new drug-delivery system that senses high oxidant levels and responds by administering just the right amount of antioxidant to restore this delicate balance.The findings are published in the journal Small.Many pharmaceuticals include specialized polymers and particles that control the timing or concentration of the drug released once administered, the researchers said. However, these additives can hamper crystallization during the manufacturing phase of some drugs – like antioxidants – causing them to dissolve in the body in an uncontrolled manner.”We saw an opportunity here to develop a different kind of drug-delivery system that could sense the level of oxidant in a system and respond by administering antioxidant as needed,” said chemical and biomolecular engineering professor and study co-author Hyunjoon Kong.Kong and his team found a way to assemble crystals of catechin – the bright green antioxidant found in green tea – using a polymer that can sense when oxidant concentrations become too high. The researchers tested the responsiveness of the resulting catechin crystal-containing polymer in the common freshwater planktonic crustacean Daphnia magna, the water flea.”Heart rate is an indication of the extent to which potentially toxic chemicals influence physiology in water fleas,” Kong said. “Daphnids are often used to monitor environmental impacts on ecological systems, and because their hearts are similar to those of vertebrates, they are also used to evaluate the efficacy of cardioprotective drugs.”Related StoriesChronic inflammation removes motivation by reducing dopamine in the brainCancer incidence among children and young adults with congenital heart diseaseStudy measures antioxidant levels in edible insectsThe researchers exposed the daphnids to water contaminated with sublethal concentrations of the natural oxidant hydrogen peroxide while monitoring their heart rate. They found that the daphnids’ mean heart rates dropped from 348 to 290 and 277 beats per minute, depending on the concentration of hydrogen peroxide used.When the team added the new catechin crystal assembled with polymer to the experiment, the water fleas eventually recovered a close-to-normal heart rate.Beyond the potential pharmaceutical uses for the new polymer, Kong’s group is looking into its use for curtailing the impact of highly oxidizing chemicals in natural waterways.”Hydrogen peroxide is often used to clean water fouled by excessive algae, and this raises concern about how the oxidant may be affecting living organisms in water,” he said. “We think this new antioxidant-delivery system could be used to address the problem of over-oxidized natural waters.”The researchers plan to push ahead with developing the polymer for pharmaceutical and environmental uses. “This study proved a concept, but we have more work to do,” Kong said. “There is concern over the safety of the specific polymer we used – polyethylenimine diselenide – but we are getting close to finding a viable replacement.”last_img read more

first_img Explore further France is ready to consider cutting its stake in Renault in the interests of consolidating the automaker’s alliance with Nissan, Finance Minister Bruno Le Maire said Saturday. © 2019 AFP This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Renault tries to reassure partner Nissan on Fiat planscenter_img Citation: France ready to cut Renault stake to shore up Nissan partnership: minister (2019, June 8) retrieved 17 July 2019 from https://phys.org/news/2019-06-france-ready-renault-staketo-shore.html Le Maire said Renault should concentrate on forging closer ties with Nissan before seeking other alliances He was speaking in Japan after Italian-US carmaker Fiat Chrysler pulled the plug on its proposed merger with Renault, saying negotiations had become “unreasonable” due to political resistance in Paris.In an interview with AFP on the sidelines of the G20 finance ministers meeting in Japan, Le Maire said Paris might consider reducing the state’s 15-percent stake in Renault if it led to a “more solid” alliance between the Japanese and French firms.”We can reduce the state’s stake in Renault’s capital. This is not a problem as long as, at the end of the process, we have a more solid auto sector and a more solid alliance between the two great car manufacturers Nissan and Renault,” he told AFP.Last week, FCA stunned the auto world with a proposed “merger of equals” with Renault that would—together with Renault’s Japanese partners Nissan and Mitsubishi Motors—create a car giant spanning the globe. The combined group would have been by far the world’s biggest, with total sales of some 15 million vehicles, compared to both Volkswagen and Toyota, which sell around 10.6 million apiece.But the deal collapsed suddenly on Thursday, with FCA laying the blame at the door of Paris. “It has become clear that the political conditions in France do not currently exist for such a combination to proceed successfully,” FCA said in a statement.Le Maire said Renault should concentrate on forging closer ties with its Japanese partner Nissan before seeking other alliances.Things need to be done “in the right order…. First the alliance (between Nissan and Renault) should be consolidated and then consolidation (more generally) and not one before the other.””Otherwise, everything risks collapsing like a house of cards,” he warned.The minister said it would be up to the bosses of Renault and Nissan to decide how to push the alliance forward as ties between the two firms have been strained after the shock arrest of former boss Carlos Ghosn.Renault is pushing for a full merger between the pair but there is deep scepticism of the plan at Nissan.There were varied reactions from the French unions Saturday.”The government is behaving like the agent of the big shareholders, favouring short-term profit to the detriment of the interests of the country,” said Fabien Gache, of the CGT union.Cutting the state’s share in Renault was abandoning its responsibility in the country’s auto industry, he argued.Franck Daout of the CFDT union said it backed a three-way alliance between Renault, Nissan and Japan’s Mitsubishi—but not one between Nissan and Renault until the alliance had reached a “safe and sustainable maturity”.last_img read more

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